A Review of Platelet-Rich Plasma: History, Biology, Mechanism of Action, and Classification

Overview

Journal Skin Appendage Disord

Specialty Dermatology

Date 2018 Feb 20

PMID 29457008

Citations 202

Authors

Rubina Alves

Ramon Grimalt

Affiliations

Soon will be listed here.

Abstract

Platelet-rich plasma (PRP) is currently used in different medical fields. The interest in the application of PRP in dermatology has recently increased. It is being used in several different applications as in tissue regeneration, wound healing, scar revision, skin rejuvenating effects, and alopecia. PRP is a biological product defined as a portion of the plasma fraction of autologous blood with a platelet concentration above the baseline. It is obtained from the blood of patients collected before centrifugation. The knowledge of the biology, mechanism of action, and classification of the PRP should help clinicians better understand this new therapy and to easily sort and interpret the data available in the literature regarding PRP. In this review, we try to provide useful information for a better understanding of what should and should not be treated with PRP.

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