Synaptic E-I Balance Underlies Efficient Neural Coding

Overview

Journal Front Neurosci

Date 2018 Feb 20

PMID 29456491

Citations 65

Authors

Shanglin Zhou

Yuguo Yu

Affiliations

Soon will be listed here.

Abstract

Both theoretical and experimental evidence indicate that synaptic excitation and inhibition in the cerebral cortex are well-balanced during the resting state and sensory processing. Here, we briefly summarize the evidence for how neural circuits are adjusted to achieve this balance. Then, we discuss how such excitatory and inhibitory balance shapes stimulus representation and information propagation, two basic functions of neural coding. We also point out the benefit of adopting such a balance during neural coding. We conclude that excitatory and inhibitory balance may be a fundamental mechanism underlying efficient coding.

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