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Defective Endogenous Pain Modulation in Fibromyalgia: A Meta-Analysis of Temporal Summation and Conditioned Pain Modulation Paradigms

Overview
Journal J Pain
Specialties Neurology
Psychiatry
Date 2018 Feb 19
PMID 29454976
Citations 83
Authors
Affiliations
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Abstract

Perspective: This novel meta-analysis provides evidence for defective endogenous pain modulation in FM patients. We explored the effect of covariates on between-study variability in these paradigms. These biomarkers may aid in diagnosis, and treatment of patients. However, validation requires further investigation under strict methodological settings, and into individual patient covariates.

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