Does Hope Matter? Associations Among Self-Reported Hope, Anxiety, and Health-Related Quality of Life in Children and Adolescents with Cancer

Overview

Journal J Clin Psychol Med Settings

Publisher Springer

Specialty Psychology

Date 2018 Feb 18

PMID 29453505

Citations 14

Authors

Ana Rita Martins

Carla Crespo

Agata Salvador

Susana Santos

Carlos Carona

Maria Cristina Canavarro

Affiliations

Soon will be listed here.

Abstract

This study aimed to examine the direct and indirect effects of hope on health-related quality of life (HRQoL) via anxiety of children/adolescents with cancer. We proposed to test if the mediation model was moderated by the child/adolescent's treatment status. The participants were 211 children/adolescents diagnosed with cancer, divided into two clinical groups according to treatment status: 97 patients on-treatment and 114 off-treatment. Self-reported questionnaires measured the youths' hope, anxiety, and HRQoL perceptions. The results revealed that children/adolescents on- and off-treatment only differed in levels of HRQoL, with a more compromised HRQoL found for the on-treatment group. Hope was positively associated with HRQoL, directly and indirectly via anxiety reduction. Moreover, only the association between anxiety and HRQoL was moderated by clinical group, revealing stronger associations for on-treatment patients. Findings highlight the importance of hope as a decisive resource in pediatric cancer adaptation, which may be strategically targeted in psycho-oncological interventions.

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References

Jurbergs N, Russell K, Long A, Phipps S . Adaptive style and differences in parent and child report of health-related quality of life in children with cancer. Psychooncology. 2007; 17(1):83-90. DOI: 10.1002/pon.1195. View

Varni J, Burwinkle T, Lane M . Health-related quality of life measurement in pediatric clinical practice: an appraisal and precept for future research and application. Health Qual Life Outcomes. 2005; 3:34. PMC: 1156928. DOI: 10.1186/1477-7525-3-34. View

Siegel R, DeSantis C, Virgo K, Stein K, Mariotto A, Smith T . Cancer treatment and survivorship statistics, 2012. CA Cancer J Clin. 2012; 62(4):220-41. DOI: 10.3322/caac.21149. View

Affleck G, Tennen H . Construing benefits from adversity: adaptational significance and dispositional underpinnings. J Pers. 1996; 64(4):899-922. DOI: 10.1111/j.1467-6494.1996.tb00948.x. View

Bullinger M, Brutt A, Erhart M, Ravens-Sieberer U . Psychometric properties of the KINDL-R questionnaire: results of the BELLA study. Eur Child Adolesc Psychiatry. 2009; 17 Suppl 1:125-32. DOI: 10.1007/s00787-008-1014-z. View

Hinds P, Gattuso J, Billups C, West N, Wu J, Rivera C . Aggressive treatment of non-metastatic osteosarcoma improves health-related quality of life in children and adolescents. Eur J Cancer. 2009; 45(11):2007-14. PMC: 2820559. DOI: 10.1016/j.ejca.2009.04.020. View

Noll R, Kozlowski K, Gerhardt C, Vannatta K, Taylor J, Passo M . Social, emotional, and behavioral functioning of children with juvenile rheumatoid arthritis. Arthritis Rheum. 2000; 43(6):1387-96. DOI: 10.1002/1529-0131(200006)43:6<1387::AID-ANR24>3.0.CO;2-C. View

Woodgate R, Degner L . "Nothing is carved in stone!": uncertainty in children with cancer and their families. Eur J Oncol Nurs. 2003; 6(4):191-202; discussion 203-4. DOI: 10.1054/ejon.2002.0220. View

Preacher K, Hayes A . Asymptotic and resampling strategies for assessing and comparing indirect effects in multiple mediator models. Behav Res Methods. 2008; 40(3):879-91. DOI: 10.3758/brm.40.3.879. View

10.

Neville K . Psychological distress in adolescents with cancer. J Pediatr Nurs. 1996; 11(4):243-51. DOI: 10.1016/S0882-5963(96)80097-2. View

11.

Varni J, Limbers C, Burwinkle T . Impaired health-related quality of life in children and adolescents with chronic conditions: a comparative analysis of 10 disease clusters and 33 disease categories/severities utilizing the PedsQL 4.0 Generic Core Scales. Health Qual Life Outcomes. 2007; 5:43. PMC: 1964786. DOI: 10.1186/1477-7525-5-43. View

12.

Lee E . Fatigue and hope: relationships to psychosocial adjustment in Korean women with breast cancer. Appl Nurs Res. 2001; 14(2):87-93. DOI: 10.1053/apnr.2001.22374. View

13.

Eiser C, Hill J, Vance Y . Examining the psychological consequences of surviving childhood cancer: systematic review as a research method in pediatric psychology. J Pediatr Psychol. 2000; 25(6):449-60. DOI: 10.1093/jpepsy/25.6.449. View

14.

Herth K . The relationship between level of hope and level of coping response and other variables in patients with cancer. Oncol Nurs Forum. 1989; 16(1):67-72. View

15.

Essig S, VON DER Weid N, Strippoli M, Rebholz C, Michel G, Rueegg C . Health-related quality of life in long-term survivors of relapsed childhood acute lymphoblastic leukemia. PLoS One. 2012; 7(5):e38015. PMC: 3360640. DOI: 10.1371/journal.pone.0038015. View

16.

Shankar S, Robison L, Jenney M, Rockwood T, Wu E, Feusner J . Health-related quality of life in young survivors of childhood cancer using the Minneapolis-Manchester Quality of Life-Youth Form. Pediatrics. 2005; 115(2):435-42. DOI: 10.1542/peds.2004-0649. View

17.

Kazak A, Hocking M, Ittenbach R, Meadows A, Hobbie W, DeRosa B . A revision of the intensity of treatment rating scale: classifying the intensity of pediatric cancer treatment. Pediatr Blood Cancer. 2011; 59(1):96-9. PMC: 3223269. DOI: 10.1002/pbc.23320. View

18.

Herth K, Cutcliffe J . The concept of hope in nursing 6: research/education/policy/practice. Br J Nurs. 2003; 11(21):1404-11. DOI: 10.12968/bjon.2002.11.21.12277. View

19.

Elkin T, Phipps S, Mulhern R, Fairclough D . Psychological functioning of adolescent and young adult survivors of pediatric malignancy. Med Pediatr Oncol. 1997; 29(6):582-8. DOI: 10.1002/(sici)1096-911x(199712)29:6<582::aid-mpo13>3.0.co;2-8. View

20.

Landolt M, Vollrath M, Niggli F, Gnehm H, Sennhauser F . Health-related quality of life in children with newly diagnosed cancer: a one year follow-up study. Health Qual Life Outcomes. 2006; 4:63. PMC: 1590012. DOI: 10.1186/1477-7525-4-63. View