Olfactory Neuroblastoma

Overview

Journal Curr Oncol Rep

Publisher Current Science

Specialty Oncology

Date 2018 Feb 8

PMID 29411144

Citations 26

Authors

Ahmed S Abdelmeguid

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: To provide a comprehensive review of the literature focusing on the recent advances in the diagnosis and management of olfactory neuroblastoma.

Recent Findings: Multimodality treatment is usually recommended for the majority of ONB cases. Recent advances in surgical approaches include the evolving role of endonasal endoscopic surgical resection and reconstruction. The introduction of new conformal radiation techniques has improved the outcomes and reduced treatment-related toxicity to important structures such as the eye and the brain. The role of neoadjuvant and adjuvant chemotherapy is yet to be defined. In the last two decades, there have been advances in surgical techniques with endoscopic approaches, either alone or in combination with craniotomy, gradually replacing the open traditional approaches. Prolonged surveillance is recommended for ONB due to late recurrences associated with that tumor. The role of chemotherapy and elective neck irradiation is still controversial and needs more studies to investigate their optimal role.

Citing Articles

An Uncommon Encounter: Metastatic Olfactory Neuroblastoma in an Adult Male.

Kalfoutzou A, Restemi A, Rapti C, Chaleplidis N, Bagiokou E, Bartzi D Cureus. 2024; 16(11):e73105.

PMID: 39650873 PMC: 11621874. DOI: 10.7759/cureus.73105.

Single-cell transcriptomic landscape deciphers olfactory neuroblastoma subtypes and intra-tumoral heterogeneity.

Yang J, Song X, Zhang H, Liu Q, Wei R, Guo L Nat Cancer. 2024; 5(12):1919-1939.

PMID: 39543363 DOI: 10.1038/s43018-024-00855-5.

Endoscopy-assisted medial canthus incision for olfactory neuroblastoma: a case report.

Li Y, Zhao X, Tao Y World J Surg Oncol. 2024; 22(1):163.

PMID: 38909260 PMC: 11193278. DOI: 10.1186/s12957-024-03448-9.

Olfactory Neuroblastoma Causing Cushing's Syndrome Due to the Ectopic Adrenocorticotropic Hormone (ACTH) Secretion: A Case Report.

Alsarari A, Abdulkader A, Farooqi W, Al-Shibani S, Al Khuwaitir T Cureus. 2024; 16(3):e56434.

PMID: 38638776 PMC: 11024664. DOI: 10.7759/cureus.56434.

A case of olfactory neuroblastoma that presented with olfactory dysfunction after a COVID-19 diagnosis.

Kim K, Min H Heliyon. 2023; 9(11):e22311.

PMID: 38053881 PMC: 10694305. DOI: 10.1016/j.heliyon.2023.e22311.

References

Morita A, Ebersold M, Olsen K, Foote R, Lewis J, Quast L . Esthesioneuroblastoma: prognosis and management. Neurosurgery. 1993; 32(5):706-14; discussion 714-5. DOI: 10.1227/00006123-199305000-00002. View

Demiroz C, Gutfeld O, Aboziada M, Brown D, Marentette L, Eisbruch A . Esthesioneuroblastoma: is there a need for elective neck treatment?. Int J Radiat Oncol Biol Phys. 2011; 81(4):e255-61. DOI: 10.1016/j.ijrobp.2011.03.036. View

Lund V, Howard D, Wei W, Spittle M . Olfactory neuroblastoma: past, present, and future?. Laryngoscope. 2003; 113(3):502-7. DOI: 10.1097/00005537-200303000-00020. View

Plasencia Y, Boronat Cortes M, Marrero Arencibia D, Montenegro Damaso T, Contreras I, Ojeda Pino A . Esthesioneuroblastoma recurrence presenting as a syndrome of inappropriate antidiuretic hormone secretion. Head Neck. 2006; 28(12):1142-6. DOI: 10.1002/hed.20352. View

Nishimura H, Ogino T, Kawashima M, Nihei K, Arahira S, Onozawa M . Proton-beam therapy for olfactory neuroblastoma. Int J Radiat Oncol Biol Phys. 2007; 68(3):758-62. DOI: 10.1016/j.ijrobp.2006.12.071. View

Rimmer J, Lund V, Beale T, Wei W, Howard D . Olfactory neuroblastoma: a 35-year experience and suggested follow-up protocol. Laryngoscope. 2013; 124(7):1542-9. DOI: 10.1002/lary.24562. View

Su S, Kupferman M, DeMonte F, Levine N, Raza S, Hanna E . Endoscopic resection of sinonasal cancers. Curr Oncol Rep. 2014; 16(2):369. DOI: 10.1007/s11912-013-0369-6. View

Su S, Bell D, Hanna E . Esthesioneuroblastoma, neuroendocrine carcinoma, and sinonasal undifferentiated carcinoma: differentiation in diagnosis and treatment. Int Arch Otorhinolaryngol. 2015; 18(Suppl 2):S149-56. PMC: 4399581. DOI: 10.1055/s-0034-1390014. View

Diaz Jr E, Johnigan 3rd R, Pero C, El-Naggar A, Roberts D, Barker J . Olfactory neuroblastoma: the 22-year experience at one comprehensive cancer center. Head Neck. 2005; 27(2):138-49. DOI: 10.1002/hed.20127. View

10.

Suriano M, de Vincentiis M, Colli A, Benfari G, Mascelli A, Gallo A . Endoscopic treatment of esthesioneuroblastoma: a minimally invasive approach combined with radiation therapy. Otolaryngol Head Neck Surg. 2007; 136(1):104-7. DOI: 10.1016/j.otohns.2006.04.021. View

11.

Faragalla H, Weinreb I . Olfactory neuroblastoma: a review and update. Adv Anat Pathol. 2009; 16(5):322-31. DOI: 10.1097/PAP.0b013e3181b544cf. View

12.

Gallia G, Reh D, Salmasi V, Blitz A, Koch W, Ishii M . Endonasal endoscopic resection of esthesioneuroblastoma: the Johns Hopkins Hospital experience and review of the literature. Neurosurg Rev. 2011; 34(4):465-75. DOI: 10.1007/s10143-011-0329-2. View

13.

Josephs L, Jones L, Marenette L, McKeever P . Cushing's Syndrome: An Unusual Presentation of Olfactory Neuroblastoma. Skull Base. 2008; 18(1):73-6. PMC: 2435464. DOI: 10.1055/s-2007-994291. View

14.

Dulguerov P, Allal A, Calcaterra T . Esthesioneuroblastoma: a meta-analysis and review. Lancet Oncol. 2002; 2(11):683-90. DOI: 10.1016/S1470-2045(01)00558-7. View

15.

Rosenthal D, Barker Jr J, El-Naggar A, Glisson B, Kies M, Diaz Jr E . Sinonasal malignancies with neuroendocrine differentiation: patterns of failure according to histologic phenotype. Cancer. 2004; 101(11):2567-73. DOI: 10.1002/cncr.20693. View

16.

Bachar G, Goldstein D, Shah M, Tandon A, Ringash J, Pond G . Esthesioneuroblastoma: The Princess Margaret Hospital experience. Head Neck. 2008; 30(12):1607-14. DOI: 10.1002/hed.20920. View

17.

Saade R, Hanna E, Bell D . Prognosis and biology in esthesioneuroblastoma: the emerging role of Hyams grading system. Curr Oncol Rep. 2014; 17(1):423. DOI: 10.1007/s11912-014-0423-z. View

18.

Koo B, An J, Jeon K, Choi S, Cho Y, Jang H . Two cases of ectopic adrenocorticotropic hormone syndrome with olfactory neuroblastoma and literature review. Endocr J. 2008; 55(3):469-75. DOI: 10.1507/endocrj.k07e-005. View

19.

Howell M, Branstetter 4th B, Snyderman C . Patterns of regional spread for esthesioneuroblastoma. AJNR Am J Neuroradiol. 2011; 32(5):929-33. PMC: 7965541. DOI: 10.3174/ajnr.A2401. View

20.

Bell D, Saade R, Roberts D, Ow T, Kupferman M, DeMonte F . Prognostic utility of Hyams histological grading and Kadish-Morita staging systems for esthesioneuroblastoma outcomes. Head Neck Pathol. 2014; 9(1):51-9. PMC: 4382491. DOI: 10.1007/s12105-014-0547-3. View