» Articles » PMID: 29392135

MiRNAs in Prediction of Prognosis in Clear Cell Renal Cell Carcinoma

Overview
Journal Biomed Res Int
Publisher Wiley
Date 2018 Feb 3
PMID 29392135
Citations 16
Authors
Affiliations
Soon will be listed here.
Abstract

Renal cell carcinoma (RCC) is the most common type of urinary malignancy. Clear cell renal cell carcinoma (ccRCC) is the predominant RCC subtype, accounting for 70-80% of RCC. In recent years, miRNAs have been found to be closely associated with the outcome of the patients with ccRCC. In this review, we summarize recent advances in research exploring the role of miRNAs in predicting prognosis in patients with ccRCC.

Citing Articles

Circular RNA circDVL1 inhibits clear cell renal cell carcinoma progression through the miR-412-3p/PCDH7 axis.

Wang Y, Zhang Y, Su X, Qiu Q, Yuan Y, Weng C Int J Biol Sci. 2022; 18(4):1491-1507.

PMID: 35280687 PMC: 8898370. DOI: 10.7150/ijbs.69351.


miR-25-3p protects renal tubular epithelial cells from apoptosis induced by renal IRI by targeting DKK3.

Zhang Y, Zuo X Open Life Sci. 2022; 16(1):1393-1404.

PMID: 35174294 PMC: 8812715. DOI: 10.1515/biol-2021-0127.


Down regulation of miR-30a-5p and miR-182-5p in gastric cancer: Clinical impact and survival analysis.

Soliman S, Elabd N, El-Kousy S, Awad M Biochem Biophys Rep. 2021; 27:101079.

PMID: 34355069 PMC: 8321916. DOI: 10.1016/j.bbrep.2021.101079.


MicroRNAs Targeting HIF-2α, VEGFR1 and/or VEGFR2 as Potential Predictive Biomarkers for VEGFR Tyrosine Kinase and HIF-2α Inhibitors in Metastatic Clear-Cell Renal Cell Carcinoma.

Kinget L, Roussel E, Verbiest A, Albersen M, Rodriguez-Antona C, Grana-Castro O Cancers (Basel). 2021; 13(12).

PMID: 34205829 PMC: 8235409. DOI: 10.3390/cancers13123099.


Silencing of the chemokine CXC receptor 4 (CXCR4) hampers cancer progression and increases cisplatin (DDP)-sensitivity in clear cell renal cell carcinoma (ccRCC).

Wang W, Gan Z, Liu Q, Yan S, Mulati R, Wang Y Bioengineered. 2021; 12(1):2957-2969.

PMID: 34180759 PMC: 8806489. DOI: 10.1080/21655979.2021.1943112.


References
1.
Huang Q, Ma X, Zhang X, Liu S, Ai Q, Shi T . Down-Regulated miR-30a in Clear Cell Renal Cell Carcinoma Correlated with Tumor Hematogenous Metastasis by Targeting Angiogenesis-Specific DLL4. PLoS One. 2013; 8(6):e67294. PMC: 3694928. DOI: 10.1371/journal.pone.0067294. View

2.
Teng J, Gao Y, Chen M, Wang K, Cui X, Liu Y . Prognostic value of clinical and pathological factors for surgically treated localized clear cell renal cell carcinoma. Chin Med J (Engl). 2014; 127(9):1640-4. View

3.
Chen X, Wang X, Ruan A, Han W, Zhao Y, Lu X . miR-141 is a key regulator of renal cell carcinoma proliferation and metastasis by controlling EphA2 expression. Clin Cancer Res. 2014; 20(10):2617-30. DOI: 10.1158/1078-0432.CCR-13-3224. View

4.
Chen X, Ruan A, Wang X, Han W, Wang R, Lou N . miR-129-3p, as a diagnostic and prognostic biomarker for renal cell carcinoma, attenuates cell migration and invasion via downregulating multiple metastasis-related genes. J Cancer Res Clin Oncol. 2014; 140(8):1295-304. DOI: 10.1007/s00432-014-1690-7. View

5.
Vergho D, Kneitz S, Kalogirou C, Burger M, Krebs M, Rosenwald A . Impact of miR-21, miR-126 and miR-221 as prognostic factors of clear cell renal cell carcinoma with tumor thrombus of the inferior vena cava. PLoS One. 2014; 9(10):e109877. PMC: 4184907. DOI: 10.1371/journal.pone.0109877. View