Steroid-resistant Nephrotic Syndrome: Past and Current Perspectives

Overview

Journal Pediatric Health Med Ther

Publisher Dove Medical Press

Date 2018 Feb 2

PMID 29388620

Citations 22

Authors

Noureddin Nourbakhsh

Robert H Mak

Affiliations

Soon will be listed here.

Abstract

Patients with steroid-resistant nephrotic syndrome (SRNS) represent a challenging subset of patients with nephrotic syndrome who often fail standard immunosuppression and have a higher likelihood of progressing to end-stage renal disease. Appropriate treatment of SRNS requires an adequate understanding of the historical treatment, renal histopathology, and genetics associated with the disease. The aim of this review is to present a comprehensive appraisal of the history, role of renal biopsy, genetics, and treatment of SRNS.

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