Yoga for the Management of Cancer Treatment-Related Toxicities

Overview

Journal Curr Oncol Rep

Publisher Current Science

Specialty Oncology

Date 2018 Feb 2

PMID 29388071

Citations 18

Authors

Po-Ju Lin

Luke J Peppone

Michelle C Janelsins

Supriya G Mohile

Charles S Kamen

Ian R Kleckner

Chunkit Fung

Matthew Asare

Calvin L Cole

Eva Culakova

Karen M Mustian

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: To (1) explain what yoga is, (2) summarize published literature on the efficacy of yoga for managing cancer treatment-related toxicities, (3) provide clinical recommendations on the use of yoga for oncology professionals, and (4) suggest promising areas for future research.

Recent Findings: Based on a total of 24 phase II and one phase III clinical trials, low-intensity forms of yoga, specifically gentle hatha and restorative, are feasible, safe, and effective for treating sleep disruption, cancer-related fatigue, cognitive impairment, psychosocial distress, and musculoskeletal symptoms in cancer patients receiving chemotherapy and radiation and cancer survivors. Clinicians should consider prescribing yoga for their patients suffering with these toxicities by referring them to qualified yoga professionals. More definitive phase III clinical trials are needed to confirm these findings and to investigate other types, doses, and delivery modes of yoga for treating cancer-related toxicities in patients and survivors.

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References

Vadiraja S, Rao M, Nagendra R, Nagarathna R, Rekha M, Vanitha N . Effects of yoga on symptom management in breast cancer patients: A randomized controlled trial. Int J Yoga. 2010; 2(2):73-9. PMC: 2933732. DOI: 10.4103/0973-6131.60048. View

Beck S, Dudley W, Barsevick A . Pain, sleep disturbance, and fatigue in patients with cancer: using a mediation model to test a symptom cluster. Oncol Nurs Forum. 2005; 32(3):542. DOI: 10.1188/04.ONF.E48-E55. View

Derry H, Jaremka L, Bennett J, Peng J, Andridge R, Shapiro C . Yoga and self-reported cognitive problems in breast cancer survivors: a randomized controlled trial. Psychooncology. 2014; 24(8):958-66. PMC: 4405403. DOI: 10.1002/pon.3707. View

Raghavendra R, Nagarathna R, Nagendra H, Gopinath K, Srinath B, Ravi B . Effects of an integrated yoga programme on chemotherapy-induced nausea and emesis in breast cancer patients. Eur J Cancer Care (Engl). 2007; 16(6):462-74. DOI: 10.1111/j.1365-2354.2006.00739.x. View

Mustian K, Morrow G, Carroll J, Figueroa-Moseley C, Jean-Pierre P, Williams G . Integrative nonpharmacologic behavioral interventions for the management of cancer-related fatigue. Oncologist. 2007; 12 Suppl 1:52-67. DOI: 10.1634/theoncologist.12-S1-52. View

Ancoli-Israel S, Liu L, Marler M, Parker B, Jones V, Sadler G . Fatigue, sleep, and circadian rhythms prior to chemotherapy for breast cancer. Support Care Cancer. 2005; 14(3):201-9. PMC: 1599708. DOI: 10.1007/s00520-005-0861-0. View

Parma D, Hughes D, Ghosh S, Li R, Trevino-Whitaker R, Ogden S . Effects of six months of Yoga on inflammatory serum markers prognostic of recurrence risk in breast cancer survivors. Springerplus. 2015; 4:143. PMC: 4383749. DOI: 10.1186/s40064-015-0912-z. View

Mustian K, Sprod L, Palesh O, Peppone L, Janelsins M, Mohile S . Exercise for the management of side effects and quality of life among cancer survivors. Curr Sports Med Rep. 2009; 8(6):325-30. PMC: 2875185. DOI: 10.1249/JSR.0b013e3181c22324. View

Hofman M, Ryan J, Figueroa-Moseley C, Jean-Pierre P, Morrow G . Cancer-related fatigue: the scale of the problem. Oncologist. 2007; 12 Suppl 1:4-10. DOI: 10.1634/theoncologist.12-S1-4. View

10.

Berger A, Farr L, Kuhn B, Fischer P, Agrawal S . Values of sleep/wake, activity/rest, circadian rhythms, and fatigue prior to adjuvant breast cancer chemotherapy. J Pain Symptom Manage. 2007; 33(4):398-409. PMC: 1892632. DOI: 10.1016/j.jpainsymman.2006.09.022. View

11.

Cohen L, Warneke C, Fouladi R, Rodriguez M, Chaoul-Reich A . Psychological adjustment and sleep quality in a randomized trial of the effects of a Tibetan yoga intervention in patients with lymphoma. Cancer. 2004; 100(10):2253-60. DOI: 10.1002/cncr.20236. View

12.

Palesh O, Roscoe J, Mustian K, Roth T, Savard J, Ancoli-Israel S . Prevalence, demographics, and psychological associations of sleep disruption in patients with cancer: University of Rochester Cancer Center-Community Clinical Oncology Program. J Clin Oncol. 2009; 28(2):292-8. PMC: 2815717. DOI: 10.1200/JCO.2009.22.5011. View

13.

Andrykowski M, Donovan K, Laronga C, Jacobsen P . Prevalence, predictors, and characteristics of off-treatment fatigue in breast cancer survivors. Cancer. 2010; 116(24):5740-8. PMC: 4048855. DOI: 10.1002/cncr.25294. View

14.

Servaes P, Verhagen C, Bleijenberg G . Fatigue in cancer patients during and after treatment: prevalence, correlates and interventions. Eur J Cancer. 2001; 38(1):27-43. DOI: 10.1016/s0959-8049(01)00332-x. View

15.

Schmitz K, Courneya K, Matthews C, Demark-Wahnefried W, Galvao D, Pinto B . American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Med Sci Sports Exerc. 2010; 42(7):1409-26. DOI: 10.1249/MSS.0b013e3181e0c112. View

16.

Miller K, Siegel R, Lin C, Mariotto A, Kramer J, Rowland J . Cancer treatment and survivorship statistics, 2016. CA Cancer J Clin. 2016; 66(4):271-89. DOI: 10.3322/caac.21349. View

17.

Bower J, Woolery A, Sternlieb B, Garet D . Yoga for cancer patients and survivors. Cancer Control. 2005; 12(3):165-71. DOI: 10.1177/107327480501200304. View

18.

Bower J, Ganz P, Desmond K, Rowland J, Meyerowitz B, Belin T . Fatigue in breast cancer survivors: occurrence, correlates, and impact on quality of life. J Clin Oncol. 2000; 18(4):743-53. DOI: 10.1200/JCO.2000.18.4.743. View

19.

Kovacic T, Kovacic M . Impact of relaxation training according to Yoga In Daily Life® system on perceived stress after breast cancer surgery. Integr Cancer Ther. 2010; 10(1):16-26. DOI: 10.1177/1534735410387418. View

20.

Johns S, Brown L, Beck-Coon K, Monahan P, Tong Y, Kroenke K . Randomized controlled pilot study of mindfulness-based stress reduction for persistently fatigued cancer survivors. Psychooncology. 2014; 24(8):885-93. PMC: 4331267. DOI: 10.1002/pon.3648. View