» Articles » PMID: 29387599

Psoriasis in Children

Overview
Publisher Dove Medical Press
Date 2018 Feb 2
PMID 29387599
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

The clinical presentation, disease associations, and diverse treatment modalities in overcoming the challenges of managing pediatric psoriasis have been extensively summarized in this article. An extensive literature review revealed the differences in presentation of psoriasis during infancy, childhood, and adolescence. We also summarized the latest topical, systemic, and biological modalities in treating recalcitrant psoriasis. The association of psoriasis with juvenile arthritis and obesity and the significant influence of the disease on the children's quality of life were explored. The clinical presentation of psoriasis can evolve during the child's lifespan. While many treatment modalities already exist for treating pediatric psoriasis, some of the new biologics that are approved for adult patients have not been investigated in the pediatric population and no algorithm exists for their use in this population. Large clinical studies in the future will enhance our understanding with regards to their safety and potential implications in pediatric populations.

Citing Articles

Pediatric psoriasis: Biologics and oral small molecule inhibitors in modern therapy.

Firek A, Castelo-Soccio L JAAD Rev. 2025; 3:51-56.

PMID: 39950181 PMC: 11815549. DOI: 10.1016/j.jdrv.2024.12.008.


A Rare Case of Juvenile Psoriatic Arthritis.

Dinulescu A, Prejmereanu A, Pacurar D, Neagu O, Dijmarescu I Cureus. 2024; 16(11):e72985.

PMID: 39640142 PMC: 11617492. DOI: 10.7759/cureus.72985.


Exploring comorbidity and pharmacological treatment patterns in psoriasis - a retrospective population-based cross-sectional study.

Hamgard N, Duvetorp A, Hagg A, Jerkovic Gullin S, Seifert O J Multimorb Comorb. 2023; 13:26335565231212336.

PMID: 37915465 PMC: 10617277. DOI: 10.1177/26335565231212336.


Biological Treatments for Pediatric Psoriasis: State of the Art and Future Perspectives.

Diotallevi F, Simonetti O, Rizzetto G, Molinelli E, Radi G, Offidani A Int J Mol Sci. 2022; 23(19).

PMID: 36232430 PMC: 9569815. DOI: 10.3390/ijms231911128.


Management of psoriasis in children (Review).

Branisteanu D, Georgescu S, Serban I, Pinzariu A, Boda D, Maranduca M Exp Ther Med. 2021; 22(6):1429.

PMID: 34707710 PMC: 8543441. DOI: 10.3892/etm.2021.10864.


References
1.
Ganemo A, Wahlgren C, Svensson A . Quality of life and clinical features in Swedish children with psoriasis. Pediatr Dermatol. 2011; 28(4):375-9. DOI: 10.1111/j.1525-1470.2010.01292.x. View

2.
Wright N, Piggott C, Eichenfield L . The role of biologics and other systemic agents in the treatment of pediatric psoriasis. Semin Cutan Med Surg. 2010; 29(1):20-7. DOI: 10.1016/j.sder.2010.01.003. View

3.
Zampieron A, Buja A, Fusco M, Linder D, Bortune M, Piaserico S . Quality of life in patients with scalp psoriasis. G Ital Dermatol Venereol. 2014; 150(3):309-16. View

4.
Steele J, Choi C, Kwong P . Topical tacrolimus in the treatment of inverse psoriasis in children. J Am Acad Dermatol. 2005; 53(4):713-6. DOI: 10.1016/j.jaad.2005.05.036. View

5.
Pereira T, Vieira A, Fernandes J, Sousa-Basto A . Cyclosporin A treatment in severe childhood psoriasis. J Eur Acad Dermatol Venereol. 2006; 20(6):651-6. DOI: 10.1111/j.1468-3083.2006.01562.x. View