Psychopathological Profile and Quality of Life of Patients with Oral Lichen Planus

Overview

Journal J Appl Oral Sci

Specialty Dentistry

Date 2018 Jan 25

PMID 29364344

Citations 21

Authors

Malgorzata Radwan-Oczko

Edyta Zwyrtek

Joanna Elzbieta Owczarek

Dorota Szczesniak

Affiliations

Soon will be listed here.

Abstract

Oral lichen planus (OLP) is a chronic, multifocal, sometimes painful, inflammatory disease of the oral mucosa. OLP can predispose development of psycho-emotional disorders. Until now, the relationship between the severity of lichen planus and the psychological profile of patients (psychological well-being, perceived stress and pain coping strategies) has never been studied. Study was conducted on 42 OLP patients. Number of sites involved, severity and activity score of OLP were evaluated. Psychological tests were used to evaluate patients' psycho-emotional condition. The mean duration time of symptomatic OLP was 43 months. We detected that the longer the duration of subjective symptoms, the poorer the quality of life and the higher the level of perceived stress (PSS). Also, the higher the PSS results, the greater the anxiety and depression on Hospital Anxiety and Depression Scale (HADS). Likewise, higher level of depression in HADS was strongly correlated with worse quality of life. (p≤0.05). In this study, we detected a relationship between duration of the disease, level of perceived stress and quality of life. The longer the disease lasts, the higher it tends to catastrophize. This may influence development or increase of the anxiety and depression and may decrease patients' quality of life.

Citing Articles

Saliva and serum biomarkers in oral diseases: A case-control study.

Al Shaar A, Hamadeh O, Ali A Medicine (Baltimore). 2025; 103(52):e41072.

PMID: 39969370 PMC: 11688012. DOI: 10.1097/MD.0000000000041072.

Factors Impacting Quality of Life in a Group of Iranian Patients in Chronic Oral Mucosal Disease Following Treatment?.

Shooriabi M, Mousavy S, Kaabomeir F, Jafari E Clin Exp Dent Res. 2024; 10(4):e922.

PMID: 39205397 PMC: 11358203. DOI: 10.1002/cre2.922.

CXCL9, CXCL10, and CCL19 synergistically recruit T lymphocytes to skin in lichen planus.

Kersh A, Sati S, Huang J, Murphy C, Ahart O, Leung T JCI Insight. 2024; 9(20).

PMID: 39190494 PMC: 11533982. DOI: 10.1172/jci.insight.179899.

A New Scoring System of Oral Lichen Planus.

Chaitanya N, Chintada S, Priya S, Hashim N, Mohammed R, Rahman M J Pharm Bioallied Sci. 2024; 16(Suppl 2):S1022-S1032.

PMID: 38882870 PMC: 11174177. DOI: 10.4103/jpbs.jpbs_1163_23.

Crossroads between Skin and Endocrine Glands: The Interplay of Lichen Planus with Thyroid Anomalies.

Radu A, Carsote M, Nistor C, Dumitrascu M, Sandru F Biomedicines. 2024; 12(1).

PMID: 38255184 PMC: 10813575. DOI: 10.3390/biomedicines12010077.

References

Eisen D . The clinical features, malignant potential, and systemic associations of oral lichen planus: a study of 723 patients. J Am Acad Dermatol. 2002; 46(2):207-14. DOI: 10.1067/mjd.2002.120452. View

Girardi C, Luz C, Cherubini K, de Figueiredo M, Tiellet Nunes M, Salum F . Salivary cortisol and dehydroepiandrosterone (DHEA) levels, psychological factors in patients with oral lichen planus. Arch Oral Biol. 2011; 56(9):864-8. DOI: 10.1016/j.archoralbio.2011.02.003. View

Preda E, Pasetti P, Caggiula S, NIDOLI G, Boggio E, Azzi R . [Oral pathology of pscyhosomatic origin. Review of the literature]. Dent Cadmos. 1990; 58(1):66-72. View

Kalkur C, Sattur A, Guttal K . Role of Depression, Anxiety and Stress in Patients with Oral Lichen Planus: A Pilot Study. Indian J Dermatol. 2015; 60(5):445-9. PMC: 4601409. DOI: 10.4103/0019-5154.159625. View

Rad M, Hashemipoor M, Mojtahedi A, Zarei M, Chamani G, Kakoei S . Correlation between clinical and histopathologic diagnoses of oral lichen planus based on modified WHO diagnostic criteria. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009; 107(6):796-800. DOI: 10.1016/j.tripleo.2009.02.020. View

Mollaoglu N . Oral lichen planus: a review. Br J Oral Maxillofac Surg. 2000; 38(4):370-7. DOI: 10.1054/bjom.2000.0335. View

Soto Araya M, Rojas Alcayaga G, Esguep A . Association between psychological disorders and the presence of Oral lichen planus, Burning mouth syndrome and Recurrent aphthous stomatitis. Med Oral. 2004; 9(1):1-7. View

Escudier M, Ahmed N, Shirlaw P, Setterfield J, Tappuni A, Black M . A scoring system for mucosal disease severity with special reference to oral lichen planus. Br J Dermatol. 2007; 157(4):765-70. DOI: 10.1111/j.1365-2133.2007.08106.x. View

Wenger N, Mattson M, Furberg C, ELINSON J . Assessment of quality of life in clinical trials of cardiovascular therapies. Am J Cardiol. 1984; 54(7):908-13. DOI: 10.1016/s0002-9149(84)80232-5. View

10.

Cohen S, Kamarck T, Mermelstein R . A global measure of perceived stress. J Health Soc Behav. 1983; 24(4):385-96. View

11.

Carrozzo M, Scally K . Oral manifestations of hepatitis C virus infection. World J Gastroenterol. 2014; 20(24):7534-43. PMC: 4069285. DOI: 10.3748/wjg.v20.i24.7534. View

12.

Valter K, Vucicevic Boras V, Buljan D, Vidovic Juras D, Susic M, Gabric Panduric D . The influence of psychological state on oral lichen planus. Acta Clin Croat. 2013; 52(2):145-9. View

13.

Klocek M, Kawecka-Jaszcz K . [Quality of life in patients with essential arterial hypertension. Part II: The effect of clinical factors]. Przegl Lek. 2003; 60(2):101-6. View

14.

Chaudhary S . Psychosocial stressors in oral lichen planus. Aust Dent J. 2005; 49(4):192-5. DOI: 10.1111/j.1834-7819.2004.tb00072.x. View

15.

Zigmond A, SNAITH R . The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983; 67(6):361-70. DOI: 10.1111/j.1600-0447.1983.tb09716.x. View

16.

Ivanovski K, Nakova M, Warburton G, Pesevska S, Filipovska A, Nares S . Psychological profile in oral lichen planus. J Clin Periodontol. 2005; 32(10):1034-40. DOI: 10.1111/j.1600-051X.2005.00829.x. View

17.

Klocek M, Kawecka-Jaszcz K . [Quality of life in patients with essential arterial hypertension. Part I: The effect o socio-demographic factors ]. Przegl Lek. 2003; 60(2):92-100. View

18.

van der Meij E, Schepman K, van der Waal I . The possible premalignant character of oral lichen planus and oral lichenoid lesions: a prospective study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2003; 96(2):164-71. DOI: 10.1016/s1079-2104(03)00305-6. View

19.

Roopashree M, Gondhalekar R, Shashikanth M, George J, Thippeswamy S, Shukla A . Pathogenesis of oral lichen planus--a review. J Oral Pathol Med. 2010; 39(10):729-34. DOI: 10.1111/j.1600-0714.2010.00946.x. View

20.

Rosenstiel A, Keefe F . The use of coping strategies in chronic low back pain patients: relationship to patient characteristics and current adjustment. Pain. 1983; 17(1):33-44. DOI: 10.1016/0304-3959(83)90125-2. View