» Articles » PMID: 29361780

The Potential of Phytomelatonin As a Nutraceutical

Overview
Journal Molecules
Publisher MDPI
Specialty Biology
Date 2018 Jan 25
PMID 29361780
Citations 32
Authors
Affiliations
Soon will be listed here.
Abstract

Phytomelatonin (plant melatonin) is chemically related to the amino acid tryptophan and has many diverse properties. Phytomelatonin is an interesting compound due to its outstanding actions at the cellular and physiological level, especially its protective effect in plants exposed to diverse stress situations, while its vegetable origin offers many opportunities because it is a natural compound. We present an overview of its origin, its action in plants in general (particularly in plant species with high levels of phytomelatonin), and its possibilities for use as a nutraceutical with particular attention paid to the beneficial effects that it may have in human health. The differences between synthetic melatonin and phytomelatonin, according to its origin and purity, are presented. Finally, the current market for phytomelatonin and its limits and potentials are discussed.

Citing Articles

Nutrients and Nutraceuticals from L. Pomace: Biological Activities, Valorization, and Potential Applications.

Prata C, Zalambani C, Rossi F, Rossello S, Cerchiara T, Cappadone C Nutrients. 2025; 17(3).

PMID: 39940441 PMC: 11820150. DOI: 10.3390/nu17030583.


Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes in Individuals with Overweight or Obesity.

Tucker R, Kim N, Gurzell E, Mathi S, Chavva S, Senthilkumar D Nutrients. 2024; 16(23.

PMID: 39683518 PMC: 11644614. DOI: 10.3390/nu16234125.


Melatonin's Impact on Wound Healing.

Sohn E, Kim S, Lee S Antioxidants (Basel). 2024; 13(10).

PMID: 39456451 PMC: 11504849. DOI: 10.3390/antiox13101197.


Mini-encyclopedia of mitochondria-relevant nutraceuticals protecting health in primary and secondary care-clinically relevant 3PM innovation.

Golubnitschaja O, Kapinova A, Sargheini N, Bojkova B, Kapalla M, Heinrich L EPMA J. 2024; 15(2):163-205.

PMID: 38841620 PMC: 11148002. DOI: 10.1007/s13167-024-00358-4.


Biosynthetic Pathways of Tryptophan Metabolites in Strain: Insights and Implications.

Kung H, Bui N, Huang B, Cheruiyot N, Chang-Chien G Int J Mol Sci. 2024; 25(9).

PMID: 38731967 PMC: 11083699. DOI: 10.3390/ijms25094747.


References
1.
Coppens P, da Silva M, Pettman S . European regulations on nutraceuticals, dietary supplements and functional foods: a framework based on safety. Toxicology. 2006; 221(1):59-74. DOI: 10.1016/j.tox.2005.12.022. View

2.
Nordlund J, LERNER A . The effects of oral melatonin on skin color and on the release of pituitary hormones. J Clin Endocrinol Metab. 1977; 45(4):768-74. DOI: 10.1210/jcem-45-4-768. View

3.
Tan D, Hardeland R, Back K, Manchester L, Alatorre-Jimenez M, Reiter R . On the significance of an alternate pathway of melatonin synthesis via 5-methoxytryptamine: comparisons across species. J Pineal Res. 2016; 61(1):27-40. DOI: 10.1111/jpi.12336. View

4.
Reiter R, Tan D, Poeggeler B, Menendez-Pelaez A, Chen L, Saarela S . Melatonin as a free radical scavenger: implications for aging and age-related diseases. Ann N Y Acad Sci. 1994; 719:1-12. DOI: 10.1111/j.1749-6632.1994.tb56817.x. View

5.
Stege P, Sombra L, Messina G, Martinez L, Silva M . Determination of melatonin in wine and plant extracts by capillary electrochromatography with immobilized carboxylic multi-walled carbon nanotubes as stationary phase. Electrophoresis. 2010; 31(13):2242-8. DOI: 10.1002/elps.200900782. View