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Abnormal Retinal Function Associated with Fenretinide, a Synthetic Retinoid

Overview
Journal Arch Ophthalmol
Specialty Ophthalmology
Date 1986 Jan 1
PMID 2935125
Citations 13
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Abstract

Five patients with basal cell carcinoma received fenretinide. Two patients while receiving the drug had evidence of abnormal rod photoreceptor function that reversed rapidly on cessation of therapy. We speculate that fenretinide may interfere with the binding of vitamin A to opsin or with the transport of vitamin A.

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