Ginseng and Obesity

Overview

Journal J Ginseng Res

Date 2018 Jan 20

PMID 29348715

Citations 35

Authors

Zhipeng Li

Geun Eog Ji

Affiliations

Soon will be listed here.

Abstract

Although ginseng has been shown to have an antiobesity effect, antiobesity-related mechanisms are complex and have not been completely elucidated. In the present study, we evaluated ginseng's effects on food intake, the digestion, and absorption systems, as well as liver, adipose tissue, and skeletal muscle in order to identify the mechanisms involved. A review of previous and studies revealed that ginseng and ginsenosides can increase energy expenditure by stimulating the adenosine monophosphate-activated kinase pathway and can reduce energy intake. Moreover, in high fat diet-induced obese and diabetic individuals, ginseng has shown a two-way adjustment effect on adipogenesis. Nevertheless, most of the previous studies into antiobesity effects of ginseng have been animal based, and there is a paucity of evidence supporting the suggestion that ginseng can exert an antiobesity effect in humans.

Citing Articles

Molecular Mechanisms behind Obesity and Their Potential Exploitation in Current and Future Therapy.

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Ginsenoside Rb1 regulates CPT1A deacetylation to inhibit intramuscular fat infiltration after rotator cuff tear.

Yin Y, Wang Z, Yang Y, Shen M, Hu H, Chen C iScience. 2024; 27(7):110331.

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Pharmacological potential of ginseng and ginsenosides in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis.

Yi Y J Ginseng Res. 2024; 48(2):122-128.

PMID: 38465218 PMC: 10920004. DOI: 10.1016/j.jgr.2023.11.003.

Therapeutic applications of ginseng for skeletal muscle-related disorder management.

Ahmad S, Chun H, Ahmad K, Choi I J Ginseng Res. 2024; 48(1):12-19.

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Ginsenoside Rc: A potential intervention agent for metabolic syndrome.

Lu Z, Mao T, Chen K, Chai L, Dai Y, Liu K J Pharm Anal. 2024; 13(12):1375-1387.

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