Systemic Multilineage Engraftment in Mice After in Utero Transplantation with Human Hematopoietic Stem Cells

Overview

Journal Blood Adv

Specialty Hematology

Date 2018 Jan 19

PMID 29344586

Citations 5

Authors

Russell G Witt

Emily M Kreger

Laura B Buckman

Patriss W Moradi

Phong T Ho

S Christopher Derderian

Perry Tsai

Chris Baker

Nathaniel Schramm

Rachel Cleary

J Victor Garcia

Tippi C MacKenzie

Affiliations

Soon will be listed here.

Abstract

IUHCT of human cord blood-derived CD34 cells into fetal NSG mice results in systemic multilineage engraftment with human cells.Preconditioning with in utero injection of an anti-c-Kit receptor antibody (ACK2) results in an improved rate of engraftment.

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