Atypical Phenotypic Aspects of Autoimmune Thyroid Disorders in Young Patients with Turner Syndrome

Overview

Journal Ital J Pediatr

Publisher Biomed Central

Specialty Pediatrics

Date 2018 Jan 19

PMID 29343299

Citations 7

Authors

Tommaso Aversa

Romina Gallizzi

Giuseppina Salzano

Giuseppina Zirilli

Filippo De Luca

Mariella Valenzise

Affiliations

Soon will be listed here.

Abstract

Conclusions: 1) In children the association with TS is able to condition a peculiar phenotypic expression of HT in terms of epidemiology, presentation course and long-term metamorphic autoimmunity; 2) by contrast, children with TS do not exhibit an atypical clinical and biochemical course of GD, but only a significantly higher prevalence of this disease.

Citing Articles

A Case of Early Diagnosis of Turner Syndrome in a Neonate.

Hemani F, Niaz S, Kumar V, Khan S, Choudry E, Ali S Cureus. 2021; 13(7):e16733.

PMID: 34513364 PMC: 8405357. DOI: 10.7759/cureus.16733.

Rash and cholestatic liver injury caused by methimazole in a woman with Turner syndrome and Graves's disease: a case report and literature review.

Zeng J, Luo F, Lin Z, Chen Y, Wang X, Song Y BMC Endocr Disord. 2021; 21(1):179.

PMID: 34479513 PMC: 8414738. DOI: 10.1186/s12902-021-00819-1.

Basedow-Graves' disease in a pediatric patient with Sticlker syndrome, a new endocrine finding to improve personalized treatment.

Onesimo R, De Rose C, Cipolla C, Della Casa S, Leoni C, Salerni A Ital J Pediatr. 2020; 46(1):178.

PMID: 33256801 PMC: 7706036. DOI: 10.1186/s13052-020-00945-x.

Autoimmune Thyroid Disease in Specific Genetic Syndromes in Childhood and Adolescence.

Kyritsi E, Kanaka-Gantenbein C Front Endocrinol (Lausanne). 2020; 11:543.

PMID: 32973676 PMC: 7466763. DOI: 10.3389/fendo.2020.00543.

Clinical case report: A case of Turner syndrome with Graves' disease.

Zhang H, Zhang X, Yang M Medicine (Baltimore). 2020; 99(11):e19518.

PMID: 32176101 PMC: 7440195. DOI: 10.1097/MD.0000000000019518.

References

Cooper G, Stroehla B . The epidemiology of autoimmune diseases. Autoimmun Rev. 2003; 2(3):119-25. DOI: 10.1016/s1568-9972(03)00006-5. View

Wasniewska M, Corrias A, Aversa T, Valenzise M, Mussa A, De Martino L . Comparative evaluation of therapy with L-thyroxine versus no treatment in children with idiopathic and mild subclinical hypothyroidism. Horm Res Paediatr. 2012; 77(6):376-81. DOI: 10.1159/000339156. View

Takasu N, Matsushita M . Changes of TSH-Stimulation Blocking Antibody (TSBAb) and Thyroid Stimulating Antibody (TSAb) Over 10 Years in 34 TSBAb-Positive Patients with Hypothyroidism and in 98 TSAb-Positive Graves' Patients with Hyperthyroidism: Reevaluation of TSBAb and.... J Thyroid Res. 2012; 2012:182176. PMC: 3359712. DOI: 10.1155/2012/182176. View

Lleo A, Moroni L, Caliari L, Invernizzi P . Autoimmunity and Turner's syndrome. Autoimmun Rev. 2011; 11(6-7):A538-43. DOI: 10.1016/j.autrev.2011.11.015. View

Grossi A, Crino A, Luciano R, Lombardo A, Cappa M, Fierabracci A . Endocrine autoimmunity in Turner syndrome. Ital J Pediatr. 2013; 39:79. PMC: 3901035. DOI: 10.1186/1824-7288-39-79. View

Jorgensen K, Rostgaard K, Bache I, Biggar R, Nielsen N, Tommerup N . Autoimmune diseases in women with Turner's syndrome. Arthritis Rheum. 2010; 62(3):658-66. DOI: 10.1002/art.27270. View

Wasniewska M, Corrias A, Salerno M, Lombardo F, Aversa T, Mussa A . Outcomes of children with hashitoxicosis. Horm Res Paediatr. 2012; 77(1):36-40. DOI: 10.1159/000334640. View

Wasniewska M, Salerno M, Corrias A, Mazzanti L, Matarazzo P, Corica D . The Evolution of Thyroid Function after Presenting with Hashimoto Thyroiditis Is Different between Initially Euthyroid Girls with and Those without Turner Syndrome. Horm Res Paediatr. 2016; 86(6):403-409. DOI: 10.1159/000452722. View

Gawlik A, Gawlik T, Januszek-Trzciakowska A, Patel H, Malecka-Tendera E . Incidence and dynamics of thyroid dysfunction and thyroid autoimmunity in girls with Turner's syndrome: a long-term follow-up study. Horm Res Paediatr. 2011; 76(5):314-20. DOI: 10.1159/000331050. View

10.

Wasniewska M, Aversa T, Salerno M, Corrias A, Messina M, Mussa A . Five-year prospective evaluation of thyroid function in girls with subclinical mild hypothyroidism of different etiology. Eur J Endocrinol. 2015; 173(6):801-8. DOI: 10.1530/EJE-15-0484. View

11.

Bondy C . Care of girls and women with Turner syndrome: a guideline of the Turner Syndrome Study Group. J Clin Endocrinol Metab. 2006; 92(1):10-25. DOI: 10.1210/jc.2006-1374. View

12.

Livadas S, Xekouki P, Fouka F, Kanaka-Gantenbein C, Kaloumenou I, Mavrou A . Prevalence of thyroid dysfunction in Turner's syndrome: a long-term follow-up study and brief literature review. Thyroid. 2005; 15(9):1061-6. DOI: 10.1089/thy.2005.15.1061. View

13.

Valenzise M, Aversa T, Corrias A, Mazzanti L, Cappa M, Ubertini G . Epidemiology, presentation and long-term evolution of Graves' disease in children, adolescents and young adults with Turner syndrome. Horm Res Paediatr. 2014; 81(4):245-50. DOI: 10.1159/000357130. View

14.

Aversa T, Lombardo F, Corrias A, Salerno M, De Luca F, Wasniewska M . In young patients with Turner or Down syndrome, Graves' disease presentation is often preceded by Hashimoto's thyroiditis. Thyroid. 2013; 24(4):744-7. DOI: 10.1089/thy.2013.0452. View

15.

Larizza D, Calcaterra V, Martinetti M . Autoimmune stigmata in Turner syndrome: when lacks an X chromosome. J Autoimmun. 2009; 33(1):25-30. DOI: 10.1016/j.jaut.2009.03.002. View

16.

Valenzise M, Aversa T, Zirilli G, Salzano G, Corica D, Santucci S . Analysis of the factors affecting the evolution over time of subclinical hypothyroidism in children. Ital J Pediatr. 2017; 43(1):2. PMC: 5209824. DOI: 10.1186/s13052-016-0322-z. View

17.

Wasniewska M, Corrias A, Arrigo T, Lombardo F, Salerno M, Mussa A . Frequency of Hashimoto's thyroiditis antecedents in the history of children and adolescents with graves' disease. Horm Res Paediatr. 2010; 73(6):473-6. DOI: 10.1159/000313395. View

18.

Bakalov V, Gutin L, Cheng C, Zhou J, Sheth P, Shah K . Autoimmune disorders in women with turner syndrome and women with karyotypically normal primary ovarian insufficiency. J Autoimmun. 2012; 38(4):315-21. PMC: 3358475. DOI: 10.1016/j.jaut.2012.01.015. View

19.

El-Mansoury M, Bryman I, Berntorp K, Hanson C, Wilhelmsen L, Landin-Wilhelmsen K . Hypothyroidism is common in turner syndrome: results of a five-year follow-up. J Clin Endocrinol Metab. 2004; 90(4):2131-5. DOI: 10.1210/jc.2004-1262. View

20.

Elsheikh M, Wass J, Conway G . Autoimmune thyroid syndrome in women with Turner's syndrome--the association with karyotype. Clin Endocrinol (Oxf). 2001; 55(2):223-6. DOI: 10.1046/j.1365-2265.2001.01296.x. View