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Opsin-like Immunoreaction in the Retinae and Pineal Organs of Four Mammalian Species

Overview
Journal Cell Tissue Res
Specialties Anatomy & Histology
Cell Biology
Date 1985 Jan 1
PMID 2934135
Citations 28
Authors
H W Korf
R G Foster
P Ekstrom
J J Schalken
Affiliations
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Abstract

Opsin-like immunoreactivity was observed in the retinae and pineal organs of the mouse, rat and guinea pig, and the pineal organ of the cat. In the retina the immunoreaction was restricted to photoreceptor cells, which displayed immunostaining in their perikarya and outer and inner segments. Distinct pinealocytes endowed with characteristic processes were labelled in the pineal organs of the mouse and cat. However, in the cat the number of immunoreactive pinealocytes was very limited. In the pineal organs of the rat and guinea pig immunoreaction was very weak and diffuse. No immunoreaction was observed when the antibody was preabsorbed with purified bovine (rhod)opsin. These findings are in accord with the results of previous studies indicating molecular similarities between retinal photoreceptors and pinealocytes in mammals.

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References
1.
Korf H, Moller M, Gery I, Zigler J, Klein D . Immunocytochemical demonstration of retinal S-antigen in the pineal organ of four mammalian species. Cell Tissue Res. 1985; 239(1):81-5. DOI: 10.1007/BF00214906. View
2.
Moller M, Glistrup O, Olsen W . Contrast enhancement of the brownish horseradish peroxidase-activated 3,3'-diaminobenzidine tetrahydrochloride reaction product in black and white photomicrography by the use of interference filters. J Histochem Cytochem. 1984; 32(1):37-42. DOI: 10.1177/32.1.6690599. View
3.
Mirshahi M, Faure J, Brisson P, Falcon J, Guerlotte J, Collin J . S-antigen immunoreactivity in retinal rods and cones and pineal photosensitive cells. Biol Cell. 1984; 52(2):195-8. DOI: 10.1111/j.1768-322x.1985.tb00336.x. View
4.
de Grip W, Daemen F, Bonting S . Isolation and purification of bovine rhodopsin. Methods Enzymol. 1980; 67:301-20. DOI: 10.1016/s0076-6879(80)67038-4. View
5.
Somers R, Klein D . Rhodopsin kinase activity in the mammalian pineal gland and other tissues. Science. 1984; 226(4671):182-4. DOI: 10.1126/science.6091271. View