BRCA Mutations and Reproduction

Overview

Journal Fertil Steril

Specialty Reproductive Medicine

Date 2018 Jan 9

PMID 29307397

Citations 24

Authors

Hagit Daum

Tamar Peretz

Neri Laufer

Affiliations

Soon will be listed here.

Abstract

Deleterious mutations in BRCA1 or BRCA2 genes have long been recognized as independent risk factors, mostly for breast and ovarian cancer. Numerous studies have evaluated the molecular processes involving these genes, the pathophysiology of BRCAness, follow up options and modes of prophylaxis. The fertility of BRCA carriers, however, has not been widely investigated. The aim of the present work is to review the literature pertaining to this issue.

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