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Phase-Amplitude Coupling: A General Mechanism for Memory Processing and Synaptic Plasticity?

Overview
Journal Neuron
Publisher Cell Press
Specialty Neurology
Date 2018 Jan 5
PMID 29301097
Citations 43
Authors
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Abstract

In this issue of Neuron, Helfrich et al. (2017) demonstrate that phase-amplitude coupling (PAC) between slow oscillations and spindles is crucial for memory consolidation, and shifts in its phase relationship may explain age-related deficits in memory performance. These results also suggest a more general function of PAC in synaptic plasticity.

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