The Assessment of P-wave Dispersion and Myocardial Repolarization Parameters in Patients with Chronic Kidney Disease

Overview

Journal Ren Fail

Publisher Informa Healthcare

Date 2017 Dec 30

PMID 29285964

Citations 3

Authors

Korhan Kollu

Lutfullah Altintepe

Cevdet Duran

Mustafa Topal

Samil Ecirli

Affiliations

Soon will be listed here.

Abstract

Objective: The risks of sudden death and cardiac arrhythmia are increased in patients with chronic kidney disease (CKD). Here, we aimed to evaluate the indicators of arrhythmias, such as p-wave dispersion (P-WD), QTc dispersion, Tp-e and Tp-e/QT ratio in patients with CKD stages 3-5 on no renal replacement therapy (RRT).

Material And Methods: One-hundred and thirty three patients with CKD stages 3-5 and 32 healthy controls were enrolled into the study. No patients received RRT. QTc dispersion, P-WD and Tp-e interval were measured using electrocardiogram and Tp-e/QT ratio was also calculated.

Results: Mean age rates were found similar in patients and controls (60.8 ± 14.2 and 61 ± 12.9 y, p = .937, respectively). Compared patients with controls, P-WD (45.85 ± 12.42 vs. 21.17 ± 6.6 msec, p < .001), QTc-min (366.99 ± 42.31 vs. 387.15 ± 20.5 msec, p < .001), QTc dispersion (71.13 ± 27.95 vs. 41.25 ± 14.55 msec, p < .001), Tp-e maximum (81.04 ± 10.34 vs. 75.49 ± 10.9 msec, p < .001), Tp-e minimum (62.25 ± 7.58 vs. 54.8 ± 6.72 msec, p < .001) and Tp-e/QTc ratio (0.19 ± 0.02 vs. 0.18 ± 0.01, p = .001) were found to be different. QTc-max and Tp-e interval were found to be similar in both groups.

Conclusion: P-WD and QTc dispersion, Tp-e interval and Tp-e/QTc ratio were found to be increased in with CKD stages 3-5 on no RRT.

Citing Articles

Electrocardiographic substrates of arrhythmias in patients with end-stage and chronic kidney diseases: a case-control study.

Yehia H, Youssef G, Gamil M, Elsaeed M, Sadek K Egypt Heart J. 2023; 75(1):13.

PMID: 36802307 PMC: 9943799. DOI: 10.1186/s43044-023-00338-5.

P-wave durations from automated electrocardiogram analysis to predict atrial fibrillation and mortality in heart failure.

Zhou J, Li A, Tan M, Lam M, Hung L, Siu R ESC Heart Fail. 2022; 10(2):872-883.

PMID: 36461637 PMC: 10053164. DOI: 10.1002/ehf2.14230.

Effect of dialysis and transplantation on myocardial repolarization parameters and P-wave dispersion in chronic kidney disease.

Akcay M, Yildirim U J Arrhythm. 2021; 37(2):348-355.

PMID: 33850576 PMC: 8022004. DOI: 10.1002/joa3.12511.

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