Multifaceted Defense Against Listeria Monocytogenes in the Gastro-Intestinal Lumen

Overview

Journal Pathogens

Date 2017 Dec 23

PMID 29271903

Citations 7

Authors

Simone Becattini

Eric G Pamer

Affiliations

Soon will be listed here.

Abstract

is a foodborne pathogen that can cause febrile gastroenteritis in healthy subjects and systemic infections in immunocompromised individuals. Despite the high prevalence of in the environment and frequent contamination of uncooked meat and poultry products, infections with this pathogen are relatively uncommon, suggesting that protective defenses in the general population are effective. In the mammalian gastrointestinal tract, a variety of defense mechanisms prevent growth, epithelial penetration and systemic dissemination. Among these defenses, colonization resistance mediated by the gut microbiota is crucial in protection against a range of intestinal pathogens, including . Here we review defined mechanisms of defense against in the lumen of the gastro-intestinal tract, with particular emphasis on protection conferred by the autochthonous microbiota. We suggest that selected probiotic species derived from the microbiota may be developed for eventual clinical use to enhance resistance against infections.

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References

Grif K, Patscheider G, Dierich M, Allerberger F . Incidence of fecal carriage of Listeria monocytogenes in three healthy volunteers: a one-year prospective stool survey. Eur J Clin Microbiol Infect Dis. 2003; 22(1):16-20. DOI: 10.1007/s10096-002-0835-9. View

Aoki S, Pamma R, Hernday A, Bickham J, Braaten B, Low D . Contact-dependent inhibition of growth in Escherichia coli. Science. 2005; 309(5738):1245-8. DOI: 10.1126/science.1115109. View

Dalton C, Austin C, Sobel J, Hayes P, Bibb W, Graves L . An outbreak of gastroenteritis and fever due to Listeria monocytogenes in milk. N Engl J Med. 1997; 336(2):100-5. DOI: 10.1056/NEJM199701093360204. View

Wagner R, Holland M, Cerniglia C . An in vitro assay to evaluate competitive exclusion products for poultry. J Food Prot. 2002; 65(5):746-51. DOI: 10.4315/0362-028x-65.5.746. View

Ooi S, Lorber B . Gastroenteritis due to Listeria monocytogenes. Clin Infect Dis. 2005; 40(9):1327-32. DOI: 10.1086/429324. View

Kobayashi K, Chamaillard M, Ogura Y, Henegariu O, Inohara N, Nunez G . Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science. 2005; 307(5710):731-4. DOI: 10.1126/science.1104911. View

Campion A, Casey P, Field D, Cotter P, Hill C, Ross R . In vivo activity of nisin A and nisin V against Listeria monocytogenes in mice. BMC Microbiol. 2013; 13:23. PMC: 3616995. DOI: 10.1186/1471-2180-13-23. View

Gahan C, Hill C . Gastrointestinal phase of Listeria monocytogenes infection. J Appl Microbiol. 2005; 98(6):1345-53. DOI: 10.1111/j.1365-2672.2005.02559.x. View

Buffie C, Bucci V, Stein R, McKenney P, Ling L, Gobourne A . Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile. Nature. 2014; 517(7533):205-8. PMC: 4354891. DOI: 10.1038/nature13828. View

10.

Saraoui T, Fall P, Leroi F, Antignac J, Chereau S, Pilet M . Inhibition mechanism of Listeria monocytogenes by a bioprotective bacteria Lactococcus piscium CNCM I-4031. Food Microbiol. 2015; 53(Pt A):70-8. DOI: 10.1016/j.fm.2015.01.002. View

11.

Zhang Q, Pan Y, Yan R, Zeng B, Wang H, Zhang X . Commensal bacteria direct selective cargo sorting to promote symbiosis. Nat Immunol. 2015; 16(9):918-26. DOI: 10.1038/ni.3233. View

12.

Harwig S, Tan L, Qu X, Cho Y, Eisenhauer P, Lehrer R . Bactericidal properties of murine intestinal phospholipase A2. J Clin Invest. 1995; 95(2):603-10. PMC: 295524. DOI: 10.1172/JCI117704. View

13.

Cabinian A, Sinsimer D, Tang M, Jang Y, Choi B, Laouar Y . Gut symbiotic microbes imprint intestinal immune cells with the innate receptor SLAMF4 which contributes to gut immune protection against enteric pathogens. Gut. 2017; 67(5):847-859. PMC: 5890651. DOI: 10.1136/gutjnl-2016-313214. View

14.

Le Blay G, Hammami R, Lacroix C, Fliss I . Stability and Inhibitory Activity of Pediocin PA-1 Against Listeria sp. in Simulated Physiological Conditions of the Human Terminal Ileum. Probiotics Antimicrob Proteins. 2016; 4(4):250-8. DOI: 10.1007/s12602-012-9111-1. View

15.

Abt M, Osborne L, Monticelli L, Doering T, Alenghat T, Sonnenberg G . Commensal bacteria calibrate the activation threshold of innate antiviral immunity. Immunity. 2012; 37(1):158-70. PMC: 3679670. DOI: 10.1016/j.immuni.2012.04.011. View

16.

Begley M, Gahan C, Hill C . Bile stress response in Listeria monocytogenes LO28: adaptation, cross-protection, and identification of genetic loci involved in bile resistance. Appl Environ Microbiol. 2002; 68(12):6005-12. PMC: 134417. DOI: 10.1128/AEM.68.12.6005-6012.2002. View

17.

MacGowan A, Bowker K, McLAUCHLIN J, Bennett P, Reeves D . The occurrence and seasonal changes in the isolation of Listeria spp. in shop bought food stuffs, human faeces, sewage and soil from urban sources. Int J Food Microbiol. 1994; 21(4):325-34. DOI: 10.1016/0168-1605(94)90062-0. View

18.

Koren O, Goodrich J, Cullender T, Spor A, Laitinen K, Backhed H . Host remodeling of the gut microbiome and metabolic changes during pregnancy. Cell. 2012; 150(3):470-80. PMC: 3505857. DOI: 10.1016/j.cell.2012.07.008. View

19.

Ho J, Shands K, Friedland G, Eckind P, Fraser D . An outbreak of type 4b Listeria monocytogenes infection involving patients from eight Boston hospitals. Arch Intern Med. 1986; 146(3):520-4. View

20.

Altenhoefer A, Oswald S, Sonnenborn U, Enders C, Schulze J, Hacker J . The probiotic Escherichia coli strain Nissle 1917 interferes with invasion of human intestinal epithelial cells by different enteroinvasive bacterial pathogens. FEMS Immunol Med Microbiol. 2004; 40(3):223-9. DOI: 10.1016/S0928-8244(03)00368-7. View