Serum Phospholipase A in Hematological Diseases

Overview

Journal Klin Wochenschr

Specialty General Medicine

Date 1989 Feb 1

PMID 2927059

Citations 2

Authors

R T Hiefinger

W G Guder

G E Hoffmann

Affiliations

Soon will be listed here.

Abstract

Inflammatory cells, e.g., neutrophils, monocytes, and macrophages are presumed to be a source of circulating phospholipase A in nonpancreatic diseases. Therefore, we investigated in a preliminary study whether serum phospholipase A activity is related to leukocyte counts in 43 patients with hematological diseases. Serum PLA activity was significantly increased in patients with Hodgkin's disease, acute monocytic leukemia, myelofibrosis with myeloid metaplasia, and polycythemia vera when compared with patients with chronic myelogenous leukemia, chronic lymphocytic leukemia, and acute myelogenous leukemia, but did not correlate with total leukocyte counts.

Citing Articles

Serum phospholipase--regulatory and pathophysiological aspects.

Hoffmann G, Guder W Klin Wochenschr. 1989; 67(3):144-8.

PMID: 2648058 DOI: 10.1007/BF01711341.

Elevation of serum phospholipase A2 in patients at an intensive care unit.

Kitagawa M, Hayakawa T, Kondo T, Shibata T, Sakai Y, Sobajima H Int J Pancreatol. 1991; 10(3-4):279-86.

PMID: 1787339 DOI: 10.1007/BF02924166.

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