The Effects of Dissolved Organic Matter and Feeding on Bioconcentration and Oxidative Stress of Ethylhexyl Dimethyl P-aminobenzoate (OD-PABA) to Crucian Carp (Carassius Auratus)

Overview

Journal Environ Sci Pollut Res Int

Publisher Springer

Specialties Environmental Health
Toxicology

Date 2017 Dec 20

PMID 29255981

Authors

Binni Ma

Guanghua Lu

Haohan Yang

Jianchao Liu

Zhenhua Yan

Matthew Nkoom

Affiliations

Soon will be listed here.

Abstract

Bioconcentration of UV filters in organisms is an important indicator for the assessment of environmental hazards. However, bioconcentration testing rarely accounts for the influence of natural aquatic environmental factors. In order to better assess the ecological risk of organic UV filters (OUV-Fs) in an actual water environment, this study determined the influences of dissolved organic matter (DOM) (0, 1, 10, and 20 mg/L) and feeding (0, 0.5, 1, and 2% body weight/d) on bioconcentration of ethylhexyl dimethyl p-aminobenzoate (OD-PABA) in various tissues of crucian carp (Carassius auratus). Moreover, oxidative stress in the fish liver caused by the OD-PABA was also investigated by measuring activities of superoxide dismutase (SOD), catalase (CAT) and glutathione S-transferase (GST), and levels of glutathione (GSH) and malondialdehyde (MDA). The bioconcentration of OD-PABA in the fish tissues was significantly decreased with the presence of DOM indicating a reduction of OD-PABA bioavailability caused by DOM. The bioconcentration factors (BCFs) decreased by 28.00~50.93% in the muscle, 72.67~96.74% in the gill, 37.84~87.72% in the liver, and 10.32~79.38% in the kidney at different DOM concentrations compared to those of the non-DOM treatments. Significant changes in SOD, CAT, GST, GSH, and MDA levels were found in the DOM- and OD-PABA-alone treatments. However, there were no significant differences in the SOD, CAT, GST, and MDA levels found when co-exposure to OD-PABA and DOM. Feeding led to lower OD-PABA concentrations in the fish tissues, and the concentrations were decreased with increasing feeding ratios. BCFs in various tissues reduced by 39.75~72.52% in the muscle, 56.86~79.73% in the gill, 66.41~87.50% in the liver, and 75.88~89.10% in the kidney, respectively. In the unfed treatments, the levels of SOD and MDA were significantly higher than those of the fed ones while GST and GSH levels were remarkably inhibited indicating the enhanced effect of starvation to oxidative stress. There was no markedly alternation of the biomarker levels observed between different fed treatments. In conclusion, our study indicated that both DOM and feeding reduced bioconcentration of OD-PABA and alleviated oxidative stress to some extent in the crucian carp.

References

Jurado A, Gago-Ferrero P, Vazquez-Sune E, Carrera J, Pujades E, Diaz-Cruz M . Urban groundwater contamination by residues of UV filters. J Hazard Mater. 2014; 271:141-9. DOI: 10.1016/j.jhazmat.2014.01.036. View

Ke R, Wang Z, Huang S, Khan S . Accurate quantification of freely dissolved organochlorine pesticides in water in the presence of dissolved organic matter using triolein-embedded cellulose acetate membrane. Anal Bioanal Chem. 2007; 387(8):2871-9. DOI: 10.1007/s00216-007-1174-6. View

Morales A, Perez-Jimenez A, Hidalgo M, Abellan E, Cardenete G . Oxidative stress and antioxidant defenses after prolonged starvation in Dentex dentex liver. Comp Biochem Physiol C Toxicol Pharmacol. 2004; 139(1-3):153-61. DOI: 10.1016/j.cca.2004.10.008. View

Akkanen J, Tuikka A, Kukkonen J . On the borderline of dissolved and particulate organic matter: partitioning and bioavailability of polycyclic aromatic hydrocarbons. Ecotoxicol Environ Saf. 2011; 78:91-8. DOI: 10.1016/j.ecoenv.2011.11.010. View

Bargar T, Alvarez D, Garrison V . Synthetic ultraviolet light filtering chemical contamination of coastal waters of Virgin Islands national park, St. John, U.S. Virgin Islands. Mar Pollut Bull. 2015; 101(1):193-199. DOI: 10.1016/j.marpolbul.2015.10.077. View

Sang Z, Leung K . Environmental occurrence and ecological risk assessment of organic UV filters in marine organisms from Hong Kong coastal waters. Sci Total Environ. 2016; 566-567:489-498. DOI: 10.1016/j.scitotenv.2016.05.120. View

Matsuo A, Playle R, Val A, Wood C . Physiological action of dissolved organic matter in rainbow trout in the presence and absence of copper: sodium uptake kinetics and unidirectional flux rates in hard and softwater. Aquat Toxicol. 2004; 70(1):63-81. DOI: 10.1016/j.aquatox.2004.07.005. View

Wang H, Wang M, Wang H, Gao J, Dahlgren R, Yu Q . Aqueous photochemical degradation of BDE-153 in solutions with natural dissolved organic matter. Chemosphere. 2016; 155:367-374. DOI: 10.1016/j.chemosphere.2016.04.071. View

Kameda Y, Kimura K, Miyazaki M . Occurrence and profiles of organic sun-blocking agents in surface waters and sediments in Japanese rivers and lakes. Environ Pollut. 2011; 159(6):1570-6. DOI: 10.1016/j.envpol.2011.02.055. View

10.

Langford K, Reid M, Fjeld E, Oxnevad S, Thomas K . Environmental occurrence and risk of organic UV filters and stabilizers in multiple matrices in Norway. Environ Int. 2015; 80:1-7. DOI: 10.1016/j.envint.2015.03.012. View

11.

Rowett C, Hutchinson T, Comber S . The impact of natural and anthropogenic Dissolved Organic Carbon (DOC), and pH on the toxicity of triclosan to the crustacean Gammarus pulex (L.). Sci Total Environ. 2016; 565:222-231. DOI: 10.1016/j.scitotenv.2016.04.170. View

12.

Tsui M, Leung H, Lam P, Murphy M . Seasonal occurrence, removal efficiencies and preliminary risk assessment of multiple classes of organic UV filters in wastewater treatment plants. Water Res. 2014; 53:58-67. DOI: 10.1016/j.watres.2014.01.014. View

13.

Rodil R, Moeder M, Altenburger R, Schmitt-Jansen M . Photostability and phytotoxicity of selected sunscreen agents and their degradation mixtures in water. Anal Bioanal Chem. 2009; 395(5):1513-24. DOI: 10.1007/s00216-009-3113-1. View

14.

Alonso M, Feo M, Corcellas C, Gago-Ferrero P, Bertozzi C, Marigo J . Toxic heritage: Maternal transfer of pyrethroid insecticides and sunscreen agents in dolphins from Brazil. Environ Pollut. 2015; 207:391-402. DOI: 10.1016/j.envpol.2015.09.039. View

15.

Wen W, Xia X, Chen X, Wang H, Zhu B, Li H . Bioconcentration of perfluoroalkyl substances by Chironomus plumosus larvae in water with different types of dissolved organic matters. Environ Pollut. 2016; 213:299-307. DOI: 10.1016/j.envpol.2016.02.018. View

16.

Pascual P, Pedrajas J, Toribio F, Lopez-Barea J, Peinado J . Effect of food deprivation on oxidative stress biomarkers in fish (Sparus aurata). Chem Biol Interact. 2003; 145(2):191-9. DOI: 10.1016/s0009-2797(03)00002-4. View

17.

Cuderman P, Heath E . Determination of UV filters and antimicrobial agents in environmental water samples. Anal Bioanal Chem. 2006; 387(4):1343-50. DOI: 10.1007/s00216-006-0927-y. View

18.

Dutta H, Adhikari S, Singh N, Roy P, Munshi J . Histopathological changes induced by malathion in the liver of a freshwater catfish, Heteropneustes fossilis (Bloch). Bull Environ Contam Toxicol. 1993; 51(6):895-900. DOI: 10.1007/BF00198287. View

19.

Gago-Ferrero P, Diaz-Cruz M, Barcelo D . Occurrence of multiclass UV filters in treated sewage sludge from wastewater treatment plants. Chemosphere. 2011; 84(8):1158-65. DOI: 10.1016/j.chemosphere.2011.04.003. View

20.

Tsui M, Leung H, Wai T, Yamashita N, Taniyasu S, Liu W . Occurrence, distribution and ecological risk assessment of multiple classes of UV filters in surface waters from different countries. Water Res. 2014; 67:55-65. DOI: 10.1016/j.watres.2014.09.013. View