Predictors of Coverage of the National Maternal Pertussis and Infant Rotavirus Vaccination Programmes in England

Overview

Journal Epidemiol Infect

Publisher Cambridge University Press

Specialties Infectious Diseases
Public Health

Date 2017 Dec 15

PMID 29239285

Citations 24

Authors

L Byrne

C Ward

J M White

G Amirthalingam

M Edelstein

Affiliations

Soon will be listed here.

Abstract

This study assessed variation in coverage of maternal pertussis vaccination, introduced in England in October 2012 in response to a national outbreak, and a new infant rotavirus vaccination programme, implemented in July 2013. Vaccine eligible patients were included from national vaccine coverage datasets and covered April 2014 to March 2015 for pertussis and January 2014 to June 2016 for rotavirus. Vaccine coverage (%) was calculated overall and by NHS England Local Team (LT), ethnicity and Index of Multiple Deprivation (IMD) quintile, and compared using binomial regression. Compared with white-British infants, the largest differences in rotavirus coverage were in 'other', white-Irish and black-Caribbean infants (-13·9%, -12·1% and -10·7%, respectively), after adjusting for IMD and LT. The largest differences in maternal pertussis coverage were in black-other and black-Caribbean women (-16·3% and -15·4%, respectively). Coverage was lowest in London LT for both programmes. Coverage decreased with increasing deprivation and was 14·0% lower in the most deprived quintile compared with the least deprived for the pertussis programme and 4·4% lower for rotavirus. Patients' ethnicity and deprivation were therefore predictors of coverage which contributed to, but did not wholly account for, geographical variation in coverage in England.

Citing Articles

'It was just the given thing to do': exploring enablers for high childhood vaccination uptake in East London's Bangladeshi community-a qualitative study.

Ali I, Bell S, Mounier-Jack S BMJ Public Health. 2025; 3(1):e001004.

PMID: 40017957 PMC: 11812862. DOI: 10.1136/bmjph-2024-001004.

Enablers to high vaccination uptake among a disadvantaged minority population: a qualitative study of the Arab population of Israel.

Essa-Hadad J, Jansen D, Vervoort J, Edelstein M Isr J Health Policy Res. 2024; 13(1):71.

PMID: 39639350 PMC: 11619086. DOI: 10.1186/s13584-024-00660-6.

Promotion and COVID-19 lockdown increase uptake of funded maternal pertussis vaccination in pharmacy: A mixed methods study.

Gauld N, Knapton C, Sinclair O, Grant C PLoS One. 2024; 19(8):e0307971.

PMID: 39208314 PMC: 11361654. DOI: 10.1371/journal.pone.0307971.

Ethnic inequities in routine childhood vaccinations in England 2006-2021: an observational cohort study using electronic health records.

Zhang C, Bankhead C, Quigley M, Kwok C, Carson C EClinicalMedicine. 2023; 65:102281.

PMID: 37965428 PMC: 10641103. DOI: 10.1016/j.eclinm.2023.102281.

Parental preferences for rotavirus vaccination for their children under 5 years old in China: A discrete choice experiment.

Ma W, Zhang L, Ren D, Meng X, Yin J, Sun Q Hum Vaccin Immunother. 2023; 19(1):2179222.

PMID: 36794417 PMC: 10026903. DOI: 10.1080/21645515.2023.2179222.

References

Henderson J, Gao H, Redshaw M . Experiencing maternity care: the care received and perceptions of women from different ethnic groups. BMC Pregnancy Childbirth. 2013; 13:196. PMC: 3854085. DOI: 10.1186/1471-2393-13-196. View

van Lier A, van de Kassteele J, de Hoogh P, Drijfhout I, de Melker H . Vaccine uptake determinants in The Netherlands. Eur J Public Health. 2013; 24(2):304-9. DOI: 10.1093/eurpub/ckt042. View

Donaldson B, Jain P, Holder B, Lindsey B, Regan L, Kampmann B . What determines uptake of pertussis vaccine in pregnancy? A cross sectional survey in an ethnically diverse population of pregnant women in London. Vaccine. 2015; 33(43):5822-5828. DOI: 10.1016/j.vaccine.2015.08.093. View

Marshall H, Clarke M, Rasiah K, Richmond P, Buttery J, Reynolds G . Predictors of disease severity in children hospitalized for pertussis during an epidemic. Pediatr Infect Dis J. 2014; 34(4):339-45. DOI: 10.1097/INF.0000000000000577. View

Baker D, Garrow A, Shiels C . Inequalities in immunisation and breast feeding in an ethnically diverse urban area: cross-sectional study in Manchester, UK. J Epidemiol Community Health. 2010; 65(4):346-52. DOI: 10.1136/jech.2008.085142. View

Amirthalingam G, Andrews N, Campbell H, Ribeiro S, Kara E, Donegan K . Effectiveness of maternal pertussis vaccination in England: an observational study. Lancet. 2014; 384(9953):1521-8. DOI: 10.1016/S0140-6736(14)60686-3. View

Brien S, Kwong J, Charland K, Verma A, Brownstein J, Buckeridge D . Neighborhood determinants of 2009 pandemic A/H1N1 influenza vaccination in Montreal, Quebec, Canada. Am J Epidemiol. 2012; 176(10):897-908. PMC: 3662406. DOI: 10.1093/aje/kws154. View

van Hoek A, Campbell H, Amirthalingam G, Andrews N, Miller E . Cost-effectiveness and programmatic benefits of maternal vaccination against pertussis in England. J Infect. 2016; 73(1):28-37. DOI: 10.1016/j.jinf.2016.04.012. View

Cheng P, Huang S, Shaw S, Kao C, Chueh H, Chang S . Factors influencing women's decisions regarding pertussis vaccine: A decision-making study in the Postpartum Pertussis Immunization Program of a teaching hospital in Taiwan. Vaccine. 2010; 28(34):5641-7. DOI: 10.1016/j.vaccine.2010.05.078. View

10.

Samad L, Tate A, Dezateux C, Peckham C, Butler N, Bedford H . Differences in risk factors for partial and no immunisation in the first year of life: prospective cohort study. BMJ. 2006; 332(7553):1312-3. PMC: 1473111. DOI: 10.1136/bmj.332.7553.1312. View

11.

Hawker J, Olowokure B, Wood A, Wilson R, Johnson R . Widening inequalities in MMR vaccine uptake rates among ethnic groups in an urban area of the UK during a period of vaccine controversy (1994-2000). Vaccine. 2007; 25(43):7516-9. DOI: 10.1016/j.vaccine.2007.08.043. View

12.

Green H, Andrews N, Letley L, Sunderland A, White J, Pebody R . Phased introduction of a universal childhood influenza vaccination programme in England: population-level factors predicting variation in national uptake during the first year, 2013/14. Vaccine. 2015; 33(22):2620-8. DOI: 10.1016/j.vaccine.2015.03.049. View

13.

Amirthalingam G, Letley L, Campbell H, Green D, Yarwood J, Ramsay M . Lessons learnt from the implementation of maternal immunization programs in England. Hum Vaccin Immunother. 2016; 12(11):2934-2939. PMC: 5137530. DOI: 10.1080/21645515.2016.1210730. View

14.

Briand V, Bonmarin I, Levy-Bruhl D . Study of the risk factors for severe childhood pertussis based on hospital surveillance data. Vaccine. 2007; 25(41):7224-32. DOI: 10.1016/j.vaccine.2007.07.020. View

15.

Wagner K, van Wijgerden J, Andrews N, Goulden K, White J . Childhood vaccination coverage by ethnicity within London between 2006/2007 and 2010/2011. Arch Dis Child. 2013; 99(4):348-53. DOI: 10.1136/archdischild-2013-304388. View

16.

Collins J, Alona I, Tooher R, Marshall H . Increased awareness and health care provider endorsement is required to encourage pregnant women to be vaccinated. Hum Vaccin Immunother. 2014; 10(10):2922-9. PMC: 5443072. DOI: 10.4161/21645515.2014.971606. View

17.

Knight M, Kurinczuk J, Spark P, Brocklehurst P . Inequalities in maternal health: national cohort study of ethnic variation in severe maternal morbidities. BMJ. 2009; 338:b542. PMC: 2654771. DOI: 10.1136/bmj.b542. View

18.

Nair M, Kurinczuk J, Knight M . Ethnic variations in severe maternal morbidity in the UK- a case control study. PLoS One. 2014; 9(4):e95086. PMC: 3990615. DOI: 10.1371/journal.pone.0095086. View