Progressive Multifocal Leukoencephalopathy

Overview

Journal Tidsskr Nor Laegeforen

Specialty General Medicine

Date 2017 Dec 13

PMID 29231623

Citations 11

Authors

Karl Bjornar Alstadhaug

Kjell-Morten Myhr

Christine Hanssen Rinaldo

Affiliations

Soon will be listed here.

Abstract

Progressive multifocal leukoencephalopathy is a rare, opportunistic infection of the central nervous system caused by the John Cunningham virus (JCV). There is no effective antiviral treatment available, and restoring immunocompetence is essential for survival. If this occurs too quickly, however, the inflammatory response may prove fatal. This is an up-to-date review of the disorder, intended for clinicians responsible for immunomodulatory therapy.

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