Acetazolamide-Induced Bilateral Ciliochoroidal Effusion Syndrome in Plateau Iris Configuration

Overview

Journal Am J Ophthalmol Case Rep

Specialty Ophthalmology

Date 2017 Dec 12

PMID 29226268

Citations 6

Authors

Xiaofei Man

Raquel Costa

Bernadete M Ayres

Sayoko E Moroi

Affiliations

Soon will be listed here.

Abstract

Purpose: Our purpose is to describe a 60-year-old male, who has plateau iris configuration and developed bilateral ciliochoroidal effusion syndrome after ingestion of acetazolamide.

Observations: Our case was a research participant in a multi-center clinical study (ClinicalTrials.gov NCT01677507). During the course of this study, he was treated with a single dose of acetazolamide (500 mg), and seven days later treated with latanoprost one drop daily at bedtime both eyes for seven days, and then was administered another dose of acetazolamide (500 mg). Several hours later he complained of blurred vision in the distance and mild headache. On examination, he had a myopic shift, intraocular pressures of 36 mmHg in right eye and 35 mmHg in left eye, shallow anterior chambers both eyes, and occluded angles by gonioscopy both eyes. An echographic exam confirmed the bilateral ciliochoroidal effusion syndrome. He was treated by no further dosing of acetazolamide and started on timolol, atropine and prednisolone. Two weeks later, the bilateral choroidal effusion and acute angle closure were resolved. Repeat echography showed plateau iris configuration.

Conclusions And Importance: To the best of our knowledge, drug-induced bilateral ciliochoroidal effusion syndrome has not been reported with acetazolamide in plateau iris configuration.

Citing Articles

Acute Myopic Shift after a Single Dose of Acetazolamide: A Case Report and Review of the Literature.

Kaisari E, Abouzeid H, Magnin L, Boeuf M, Gkaragkani E, Schalenbourg A Klin Monbl Augenheilkd. 2024; 241(4):554-558.

PMID: 38653306 PMC: 11038821. DOI: 10.1055/a-2244-6160.

Plateau Iris: A Review.

Tabatabaei S, Fakhraie G, Ansari S, Hamzeh N, Safizadeh M, Beikmarzehei A J Curr Ophthalmol. 2023; 35(1):11-16.

PMID: 37680292 PMC: 10481971. DOI: 10.4103/joco.joco_319_22.

The Ophthalmic Side Effects of Topiramate: A Review.

Mechrgui M, Kanani S Cureus. 2022; 14(8):e28513.

PMID: 36059357 PMC: 9420653. DOI: 10.7759/cureus.28513.

Acute Primary Angle Closure Caused by Plateau Iris After Ritodrine Use in a Primigravid Woman Successfully Treated With Clear-Lens Extraction: A Case Report.

Yoshida S, Yoshida M, Himori N, Kunimatsu-Sanuki S, Nakazawa T Cureus. 2022; 14(2):e22036.

PMID: 35340488 PMC: 8912943. DOI: 10.7759/cureus.22036.

Bilateral choroidal effusions after taking acetazolamide for altitude sickness.

Rothwell A, Anderson O BMJ Case Rep. 2022; 15(1).

PMID: 35039358 PMC: 8768470. DOI: 10.1136/bcr-2021-246145.

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