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Host Susceptibility to MERS-CoV Infection, a Retrospective Cohort Study of the 2015 Korean MERS Outbreak

Overview
Journal J Infect Chemother
Publisher Elsevier
Specialties Infectious Diseases
Microbiology
Pharmacology
Date 2017 Dec 11
PMID 29223614
Citations 4
Authors
Jae-Hoon Ko
Hyeri Seok
Ga Eun Park
Ji Yeon Lee
Ji Yong Lee
Sun Young Cho
Young Eun Ha
Ji-Man Kang
Yae-Jean Kim
Cheol-In Kang
Doo Ryeon Chung
Jae-Hoon Song
Kyong Ran Peck
Affiliations
Soon will be listed here.
Abstract

To evaluate host susceptibility factors to Middle East respiratory syndrome coronavirus (MERS-CoV) infection, we conducted a retrospective cohort study from the single largest exposure event of the 2015 Korean MERS outbreak. A total of 175 patients were closely exposed to a super-spreader, 26 of which were infected (14.9%). In a multivariate analysis, history of autologous stem cell transplantation (HR, 31.151; 95% CI, 5.447-178.145; P < 0.001) and tachypnea at ED (HR, 4.392; 95% CI, 1.402-13.761; P = 0.011) were significantly associated with MERS-CoV infection.

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References
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