Tuning the Interactions Between Chiral Plasmonic Films and Living cells

Overview

Journal Nat Commun

Specialty Biology

Date 2017 Dec 10

PMID 29222410

Citations 16

Authors

Xueli Zhao

Liguang Xu

Maozhong Sun

Wei Ma

Xiaoling Wu

Chuanlai Xu

Hua Kuang

Affiliations

Soon will be listed here.

Abstract

Designing chiral materials to manipulate the biological activities of cells has been an important area not only in chemistry and material science, but also in cell biology and biomedicine. Here, we introduce monolayer plasmonic chiral Au nanoparticle (NP) films modified with L- or D-penicillamine (Pen) to be developed for cell growth, differentiation, and retrieval. The monolayer films display high chiroptical activity, with circular dichroism values of 3.5 mdeg at 550 nm and 26.8 mdeg at 775 nm. The L-Pen-NP films accelerate cell proliferation, whereas the D -Pen-NP films have the opposite effect. Remote irradiation with light is chosen to noninvasively collect the cells. The results demonstrate that left circularly polarized light improves the efficiency of cell detachment up to 91.2% for L-Pen-NP films. These findings will facilitate the development of cell culture in biomedical application and help to understand natural homochirality.

Citing Articles

Chiral MoS@BC fibrous membranes selectively promote peripheral nerve regeneration.

Li M, Li X, Lv Y, Yan H, Wang X, He J J Nanobiotechnology. 2024; 22(1):337.

PMID: 38886712 PMC: 11181549. DOI: 10.1186/s12951-024-02493-6.

3D Chiral Self-Assembling Matrixes for Regulating Polarization of Macrophages and Enhance Repair of Myocardial Infarction.

Yang L, Yang L, Lu K, Su N, Li X, Guo S Adv Sci (Weinh). 2023; 10(32):e2304627.

PMID: 37767946 PMC: 10646248. DOI: 10.1002/advs.202304627.

Interface Chirality: From Biological Effects to Biomedical Applications.

Guo L, Guo Y, Wang R, Feng J, Shao N, Zhou X Molecules. 2023; 28(15).

PMID: 37570600 PMC: 10419656. DOI: 10.3390/molecules28155629.

Chirality-biased protein expression profile during early stages of bone regeneration.

Zeng Q, Zheng H, Heng B, Yao W, Yang Y, Jiang S Front Bioeng Biotechnol. 2023; 11:1217919.

PMID: 37533694 PMC: 10393040. DOI: 10.3389/fbioe.2023.1217919.

Self-assembled inorganic chiral superstructures.

Lv J, Gao X, Han B, Zhu Y, Hou K, Tang Z Nat Rev Chem. 2023; 6(2):125-145.

PMID: 37117298 DOI: 10.1038/s41570-021-00350-w.

References

Kim Y, Yeom B, Arteaga O, Yoo S, Lee S, Kim J . Reconfigurable chiroptical nanocomposites with chirality transfer from the macro- to the nanoscale. Nat Mater. 2016; 15(4):461-8. DOI: 10.1038/nmat4525. View

Zhao X, Xu L, Sun M, Ma W, Wu X, Kuang H . Gold-Quantum Dot Core-Satellite Assemblies for Lighting Up MicroRNA In Vitro and In Vivo. Small. 2016; 12(34):4662-8. DOI: 10.1002/smll.201503629. View

Giner-Casares J, Henriksen-Lacey M, Garcia I, Liz-Marzan L . Plasmonic Surfaces for Cell Growth and Retrieval Triggered by Near-Infrared Light. Angew Chem Int Ed Engl. 2015; 55(3):974-8. PMC: 4737312. DOI: 10.1002/anie.201509025. View

Shah S, Yin P, Uehara T, Chueng S, Yang L, Lee K . Guiding stem cell differentiation into oligodendrocytes using graphene-nanofiber hybrid scaffolds. Adv Mater. 2014; 26(22):3673-80. PMC: 4048813. DOI: 10.1002/adma.201400523. View

Stroh A, Tsai H, Wang L, Zhang F, Kressel J, Aravanis A . Tracking stem cell differentiation in the setting of automated optogenetic stimulation. Stem Cells. 2011; 29(1):78-88. PMC: 4182948. DOI: 10.1002/stem.558. View

Wu X, Xu L, Liu L, Ma W, Yin H, Kuang H . Unexpected chirality of nanoparticle dimers and ultrasensitive chiroplasmonic bioanalysis. J Am Chem Soc. 2013; 135(49):18629-36. DOI: 10.1021/ja4095445. View

Zhang R, Li Y, Hu B, Lu Z, Zhang J, Zhang X . Traceable Nanoparticle Delivery of Small Interfering RNA and Retinoic Acid with Temporally Release Ability to Control Neural Stem Cell Differentiation for Alzheimer's Disease Therapy. Adv Mater. 2016; 28(30):6345-52. DOI: 10.1002/adma.201600554. View

Cao B, Peng R, Li Z, Ding J . Effects of spreading areas and aspect ratios of single cells on dedifferentiation of chondrocytes. Biomaterials. 2014; 35(25):6871-81. DOI: 10.1016/j.biomaterials.2014.04.107. View

Pang J, Xiong S, Jaeckel F, Sun Z, Dunphy D, Brinker C . Free-standing, patternable nanoparticle/polymer monolayer arrays formed by evaporation induced self-assembly at a fluid interface. J Am Chem Soc. 2008; 130(11):3284-5. DOI: 10.1021/ja710994m. View

10.

Yao X, Peng R, Ding J . Effects of aspect ratios of stem cells on lineage commitments with and without induction media. Biomaterials. 2012; 34(4):930-9. DOI: 10.1016/j.biomaterials.2012.10.052. View

11.

Lilge I, Schonherr H . Block Copolymer Brushes for Completely Decoupled Control of Determinants of Cell-Surface Interactions. Angew Chem Int Ed Engl. 2016; 55(42):13114-13117. DOI: 10.1002/anie.201607078. View

12.

Chen H, Lin M, Wang C, Chang Y, Gwo S . Large-Scale Hot Spot Engineering for Quantitative SERS at the Single-Molecule Scale. J Am Chem Soc. 2015; 137(42):13698-705. DOI: 10.1021/jacs.5b09111. View

13.

Orza A, Soritau O, Olenic L, Diudea M, Florea A, Ciuca D . Electrically conductive gold-coated collagen nanofibers for placental-derived mesenchymal stem cells enhanced differentiation and proliferation. ACS Nano. 2011; 5(6):4490-503. DOI: 10.1021/nn1035312. View

14.

Solanki A, Chueng S, Yin P, Kappera R, Chhowalla M, Lee K . Axonal alignment and enhanced neuronal differentiation of neural stem cells on graphene-nanoparticle hybrid structures. Adv Mater. 2013; 25(38):5477-82. PMC: 4189106. DOI: 10.1002/adma.201302219. View

15.

Wang X, Yan C, Ye K, He Y, Li Z, Ding J . Effect of RGD nanospacing on differentiation of stem cells. Biomaterials. 2013; 34(12):2865-74. DOI: 10.1016/j.biomaterials.2013.01.021. View

16.

Silva J, Dotti C . Breaking the neuronal sphere: regulation of the actin cytoskeleton in neuritogenesis. Nat Rev Neurosci. 2002; 3(9):694-704. DOI: 10.1038/nrn918. View

17.

Hanein D, Geiger B, Addadi L . Differential adhesion of cells to enantiomorphous crystal surfaces. Science. 1994; 263(5152):1413-6. DOI: 10.1126/science.8128221. View

18.

Cho W, Kang K, Kang G, Jang M, Nam Y, Choi I . Pitch-dependent acceleration of neurite outgrowth on nanostructured anodized aluminum oxide substrates. Angew Chem Int Ed Engl. 2010; 49(52):10114-8. DOI: 10.1002/anie.201003307. View

19.

Marchesan S, Easton C, Styan K, Waddington L, Kushkaki F, Goodall L . Chirality effects at each amino acid position on tripeptide self-assembly into hydrogel biomaterials. Nanoscale. 2014; 6(10):5172-80. DOI: 10.1039/c3nr06752a. View

20.

Lin M, Chen H, Gwo S . Layer-by-layer assembly of three-dimensional colloidal supercrystals with tunable plasmonic properties. J Am Chem Soc. 2010; 132(32):11259-63. DOI: 10.1021/ja103722p. View