The Association of Congenital Neuroblastoma and Congenital Heart Disease. Is There a Common Embryologic Basis?

Overview

Journal Pediatr Radiol

Specialty Pediatrics

Date 1989 Jan 1

PMID 2922225

Citations 10

Authors

R Bellah

A DAndrea

E Darillis

K E Fellows

Affiliations

Soon will be listed here.

Abstract

Several authors have reported an association between neuroblastoma and congenital heart disease; others contend that, unlike specific well-known associations between malignancy and congenital defects (Wilm's tumor and aniridia, leukemia and Down's syndrome), no real relationship exists. We present three cases of cyanotic congenital heart disease in which subclinical neuroblastoma was found. We speculate that abnormal neural crest cell migration and development may be a common link between cardiac malformations and congenital neuroblastoma.

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Prevalence of congenital heart defects in neuroblastoma patients: a cohort study and systematic review of literature.

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Neuroblastoma with atypical metastases to cardiac and skeletal muscles: MRI features.

Faingold R, Babyn P, Yoo S, Dipchand A, Weitzman S Pediatr Radiol. 2003; 33(8):584-6.

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