Genomic Analysis of a Case of Agminated Spitz Nevi and Congenital-pattern Nevi Arising in Extensive Nevus Spilus
Overview
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Nevus spilus is a melanocytic neoplasm characterized by a tan macular background punctuated by multiple hyperpigmented macules or papules that represent various types of nevi. These include junctional and compound nevi, Spitz nevi, and rarely blue nevi. We report a unique case of widespread, multiple nevi spili giving rise to agminated Spitz nevi and congenital-pattern compound nevi. We performed genetic analysis to further characterize the mutational profile of this rare entity.
Cantisani C, Paolino G, DI Guardo A, Gomes V, Carugno A, Greco M J Clin Med. 2024; 13(3).
PMID: 38337588 PMC: 10856709. DOI: 10.3390/jcm13030894.
The Morpho-Molecular Landscape of Spitz Neoplasms.
Dal Pozzo C, Cappellesso R Int J Mol Sci. 2022; 23(8).
PMID: 35457030 PMC: 9030540. DOI: 10.3390/ijms23084211.