Circulating Tumor Cells in Head and Neck Cancer: A Review

Overview

Journal World J Otorhinolaryngol Head Neck Surg

Date 2017 Dec 6

PMID 29204555

Citations 19

Authors

Kyle P McMullen

Jeffrey J Chalmers

Jas C Lang

Pawan Kumar

Kris R Jatana

Affiliations

Soon will be listed here.

Abstract

Carcinoma of the head and neck represents 3.5% of all cancers, and the vast majority of these tumors are squamous cell carcinoma (HNSCC). With a stable overall survival rate of 50% among all stages, there is continued interested in developing measures for early detection and disease aggressiveness. Circulating tumor cells (CTCs) have been identified as a potential marker for early metastatic disease, response to treatment, and surveillance in head and neck squamous cell carcinoma. In this article, techniques of CTC detection, applications of CTC technology, and outcomes of HNSCC patients will be discussed.

Citing Articles

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CTC together with Shh and Nrf2 are prospective diagnostic markers for HNSCC.

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