Predictors of Side Effects With Long-Term Oral Appliance Therapy for Obstructive Sleep Apnea

Overview

Journal J Clin Sleep Med

Specialties Neurology
Psychiatry

Date 2017 Dec 5

PMID 29198303

Citations 13

Authors

Hitomi Ono Minagi

Kentaro Okuno

Kanji Nohara

Takayoshi Sakai

Affiliations

Soon will be listed here.

Abstract

Study Objectives: The aim of this study was to investigate the predictors of dental changes associated with long-term treatment with oral appliances (OAs) in patients with obstructive sleep apnea (OSA).

Methods: This was a retrospective study to investigate Japanese patients with OSA receiving long-term treatment with OAs. Comparisons of cephalometric analysis were carried out between the initial and follow-up assessments of dental and skeletal changes. Based on dental changes, predictors that may cause side effects were investigated.

Results: A total of 64 patients (average age at start of treatment: 57.7 ± 14.2 years, 44 males) were included in this study. The average duration of treatment was 4.3 ± 2.1 years. Over the total treatment period, there was a significant reduction in overjet (OJ) (1.5 ± 1.3 mm) and overbite (0.90 ± 1.5 mm), and an increase in the lower incisor line to the mandibular plane (3.1 ± 5.4°). A larger reduction in OJ of ≥ 1 mm was associated with treatment duration, use frequency, and mandibular advancement of the OAs. In addition to these predictive factors, the number of teeth was correlated with the amount of OJ reduction.

Conclusions: For long-term treatment with OAs, the risk of dental side effects should be considered, such as a reduction in OJ. A small number of maxillary teeth, as well as the factors associated with OAs, including treatment duration, use frequency, and mandibular advancement of the OAs, was correlated with an increased rate of OJ reduction.

Commentary: A commentary on this article appears in this issue on page 7.

Citing Articles

A Systematic Review of Oral Modifications Caused by the Prolonged Application of Continuous Positive Airway Pressure (CPAP) and Intraoral Appliances in Patients with Obstructive Sleep Apnea (OSA).

Jafarimehrabady N, Scribante A, Defabianis P, Merlati G, Vitale M Biomed Res Int. 2024; 2024:9361528.

PMID: 38435538 PMC: 10907106. DOI: 10.1155/2024/9361528.

Effect of mandibular advancement appliance use on oral and periodontal health in patients with OSA: a systematic review.

Mansour N, Saade Y, Mora F, Bouchard P, Kerner S, Carra M Sleep Breath. 2023; 28(2):1005-1017.

PMID: 38123720 DOI: 10.1007/s11325-023-02971-5.

Objectively measured adherence may affect side effects of mandibular advancement therapy in subjects with obstructive sleep apnea.

Pahkala R Sleep Breath. 2023; 28(2):813-821.

PMID: 38114783 PMC: 11136794. DOI: 10.1007/s11325-023-02959-1.

The Occlusal Side Effects of Mandibular Advancement Device Therapy in Adult Sleep Apnea Patients: A Systematic Review.

Rana A, Raut A, Mathur A Cureus. 2023; 15(11):e48682.

PMID: 38090465 PMC: 10714377. DOI: 10.7759/cureus.48682.

The role of oral appliance therapy in obstructive sleep apnoea.

Johal A, Hamoda M, Almeida F, Marklund M, Tallamraju H Eur Respir Rev. 2023; 32(168).

PMID: 37343962 PMC: 10282823. DOI: 10.1183/16000617.0257-2022.

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