» Articles » PMID: 29184821

Approach to Hypoglycemia in Infants and Children

Overview
Journal Transl Pediatr
Specialty Pediatrics
Date 2017 Nov 30
PMID 29184821
Citations 16
Authors
Affiliations
Soon will be listed here.
Abstract

Hypoglycemia is a heterogeneous disorder with many different possible etiologies, including hyperinsulinism, glycogen storage disorders, fatty acid disorders, hormonal deficiencies, and metabolic defects, among others. This condition affects newborns to adolescents, with various approaches to diagnosis and management. This paper will review current literature on the history of hypoglycemia, current discussion on the definition of hypoglycemia, as well as etiologies, diagnosis, and management.

Citing Articles

[Guide for the treatment of acute altered mental status. Iberoamerican Academy of Pediatric Neurology].

Lopez D, Espinel F, Andrade E, Aguirre A Rev Neurol. 2024; 78(8):229-235.

PMID: 38618670 PMC: 11407450. DOI: 10.33588/rn.7808.2023302.


Idiopathic ketotic hypoglycemia in children: an update.

Metwalley K, Farghaly H Ann Pediatr Endocrinol Metab. 2024; 29(3):152-155.

PMID: 38291759 PMC: 11220389. DOI: 10.6065/apem.2346156.078.


Epstein-Barr virus-acquired immunodeficiency in myalgic encephalomyelitis-Is it present in long COVID?.

Ruiz-Pablos M, Paiva B, Zabaleta A J Transl Med. 2023; 21(1):633.

PMID: 37718435 PMC: 10506247. DOI: 10.1186/s12967-023-04515-7.


Drug-induced hyperinsulinemic hypoglycemia: An update on pathophysiology and treatment.

Maines E, Urru S, Leonardi L, Fancellu E, Campomori A, Piccoli G Rev Endocr Metab Disord. 2023; 24(6):1031-1044.

PMID: 37552352 DOI: 10.1007/s11154-023-09828-y.


Congenital hypopituitarism and multiple midline defects in a newborn with non-familial Cat Eye syndrome.

Serra G, Giambrone C, Antona V, Cardella F, Carta M, Cimador M Ital J Pediatr. 2022; 48(1):170.

PMID: 36076277 PMC: 9461219. DOI: 10.1186/s13052-022-01365-9.


References
1.
Cappella M, Graziani V, Pragliola A, Sensi A, Hussain K, Muratori C . Hyperinsulinemic Hypoglycaemia in a Turner Syndrome with Ring (X). Case Rep Pediatr. 2015; 2015:561974. PMC: 4429216. DOI: 10.1155/2015/561974. View

2.
Melis D, Rossi A, Pivonello R, Del Puente A, Pivonello C, Cangemi G . Reduced bone mineral density in glycogen storage disease type III: evidence for a possible connection between metabolic imbalance and bone homeostasis. Bone. 2016; 86:79-85. DOI: 10.1016/j.bone.2016.02.012. View

3.
Fujii S, Tamai H, Kumai M, Takaichi Y, Nakagawa T, Aoki T . Impaired glucagon secretion to insulin-induced hypoglycemia in anorexia nervosa. Acta Endocrinol (Copenh). 1989; 120(5):610-5. DOI: 10.1530/acta.0.1200610. View

4.
Palladino A, Bennett M, Stanley C . Hyperinsulinism in infancy and childhood: when an insulin level is not always enough. Clin Chem. 2007; 54(2):256-63. DOI: 10.1373/clinchem.2007.098988. View

5.
Goode R, Rettiganti M, Li J, Lyle R, Whiteside-Mansell L, Barrett K . Developmental Outcomes of Preterm Infants With Neonatal Hypoglycemia. Pediatrics. 2016; 138(6). PMC: 5127066. DOI: 10.1542/peds.2016-1424. View