Assessing Predictors for the Success of GnRH Antagonist Protocol in Reproductive Women in IVF/ICSI - in Fresh Cycles

Overview

Journal Biomed Rep

Specialty Biochemistry

Date 2017 Nov 29

PMID 29181162

Citations 1

Authors

An-Cong Wang

Ying Wang

Feng-Xia Wu

Dong-Yi Zhu

Affiliations

Soon will be listed here.

Abstract

The aim of the present study was to evaluate the factors that affect the success rate of gonadotropin-releasing hormone antagonist on fertilization/intracytoplasmic sperm injection cycles. Multivariate analysis was performed to assess the factors that influence the outcomes, such as oocytes retrieved, and the success of pregnancy. The results showed that E, P on human chorionic gonadotropin (HCG) day and body mass index (BMI) were positively correlated with the number of oocytes retrieved (P=0.001, P=0.024, P=0.017, respectively). The duration of infertility as well as the luteinizing hormone on HCG day were negatively correlated with the number of oocytes (P=0.048, P=0.002, respectively). The age of the women and P on HCG day were negatively correlated with successful pregnancy (P<0.001, P=0.022). In conclusion, some parameters, such as E, P, and LH on the HCG day, as well as age and BMI, may affect treatment outcomes.

Citing Articles

The effect of luteinizing hormone changes in GnRH antagonist protocol on the outcome of controlled ovarian hyperstimulation and embryo transfer.

Zhou J, Chen J, Tang F, Ou J, Tao X, Cai L BMC Pregnancy Childbirth. 2023; 23(1):604.

PMID: 37612626 PMC: 10464317. DOI: 10.1186/s12884-023-05916-8.

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