Dispersive Solid Phase Extraction for the Analysis of Veterinary Drugs Applied to Food Samples: A Review

Overview

Journal Int J Anal Chem

Publisher Wiley

Specialty Chemistry

Date 2017 Nov 29

PMID 29181027

Citations 14

Authors

Gabriela Islas

Israel S Ibarra

Prisciliano Hernandez

Jose M Miranda

Alberto Cepeda

Affiliations

Soon will be listed here.

Abstract

To achieve analytical success, it is necessary to develop thorough clean-up procedures to extract analytes from the matrix. Dispersive solid phase extraction (DSPE) has been used as a pretreatment technique for the analysis of several compounds. This technique is based on the dispersion of a solid sorbent in liquid samples in the extraction isolation and clean-up of different analytes from complex matrices. DSPE has found a wide range of applications in several fields, and it is considered to be a selective, robust, and versatile technique. The applications of dispersive techniques in the analysis of veterinary drugs in different matrices involve magnetic sorbents, molecularly imprinted polymers, carbon-based nanomaterials, and the Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) method. Techniques based on DSPE permit minimization of additional steps such as precipitation, centrifugation, and filtration, which decreases the manipulation of the sample. In this review, we describe the main procedures used for synthesis, characterization, and application of this pretreatment technique and how it has been applied to food analysis.

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References

Castillo-Garcia M, Aguilar-Caballos M, Gomez-Hens A . A europium- and terbium-coated magnetic nanocomposite as sorbent in dispersive solid phase extraction coupled with ultra-high performance liquid chromatography for antibiotic determination in meat samples. J Chromatogr A. 2015; 1425:73-80. DOI: 10.1016/j.chroma.2015.11.048. View

Xiong L, Gao Y, Li W, Yang X, Shimo S . Simple and sensitive monitoring of β2-agonist residues in meat by liquid chromatography-tandem mass spectrometry using a QuEChERS with preconcentration as the sample treatment. Meat Sci. 2015; 105:96-107. DOI: 10.1016/j.meatsci.2015.03.013. View

Kamalabadi M, Mohammadi A, Alizadeh N . Polypyrrole nanowire as an excellent solid phase microextraction fiber for bisphenol A analysis in food samples followed by ion mobility spectrometry. Talanta. 2016; 156-157:147-153. DOI: 10.1016/j.talanta.2016.05.007. View

Ying Y, Wu Y, Wen Y, Yang T, Xu X, Wang Y . Simultaneous determination of six resorcylic acid lactones in feed using liquid chromatography-tandem mass spectrometry and multi-walled carbon nanotubes as a dispersive solid phase extraction sorbent. J Chromatogr A. 2013; 1307:41-8. DOI: 10.1016/j.chroma.2013.07.079. View

He H, Dong C, Li B, Dong J, Bo T, Wang T . Fabrication of enrofloxacin imprinted organic-inorganic hybrid mesoporous sorbent from nanomagnetic polyhedral oligomeric silsesquioxanes for the selective extraction of fluoroquinolones in milk samples. J Chromatogr A. 2014; 1361:23-33. DOI: 10.1016/j.chroma.2014.07.089. View

Zheng H, Mo J, Zhang Y, Gao Q, Ding J, Yu Q . Facile synthesis of magnetic molecularly imprinted polymers and its application in magnetic solid phase extraction for fluoroquinolones in milk samples. J Chromatogr A. 2014; 1329:17-23. DOI: 10.1016/j.chroma.2013.12.083. View

Lopes R, Reyes R, Romero-Gonzalez R, Vidal J, Garrido Frenich A . Multiresidue determination of veterinary drugs in aquaculture fish samples by ultra high performance liquid chromatography coupled to tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2012; 895-896:39-47. DOI: 10.1016/j.jchromb.2012.03.011. View

Herrera-Herrera A, Ravelo-Perez L, Hernandez-Borges J, Afonso M, Palenzuela J, Rodriguez-Delgado M . Oxidized multi-walled carbon nanotubes for the dispersive solid-phase extraction of quinolone antibiotics from water samples using capillary electrophoresis and large volume sample stacking with polarity switching. J Chromatogr A. 2011; 1218(31):5352-61. DOI: 10.1016/j.chroma.2011.06.031. View

Hu Y, Liu R, Li Y, Li G . Investigation of ractopamine-imprinted polymer for dispersive solid-phase extraction of trace beta-agonists in pig tissues. J Sep Sci. 2010; 33(13):2017-25. DOI: 10.1002/jssc.201000063. View

10.

Plossl F, Giera M, Bracher F . Multiresidue analytical method using dispersive solid-phase extraction and gas chromatography/ion trap mass spectrometry to determine pharmaceuticals in whole blood. J Chromatogr A. 2006; 1135(1):19-26. DOI: 10.1016/j.chroma.2006.09.033. View

11.

Kong X, Gao R, He X, Chen L, Zhang Y . Synthesis and characterization of the core-shell magnetic molecularly imprinted polymers (Fe₃O₄@MIPs) adsorbents for effective extraction and determination of sulfonamides in the poultry feed. J Chromatogr A. 2012; 1245:8-16. DOI: 10.1016/j.chroma.2012.04.061. View

12.

Lara F, Garcia-Campana A, Neususs C, Ales-Barrero F . Determination of sulfonamide residues in water samples by in-line solid-phase extraction-capillary electrophoresis. J Chromatogr A. 2009; 1216(15):3372-9. DOI: 10.1016/j.chroma.2009.01.097. View

13.

Qiao F, Wang M . Preparation of selective magnetic dispersive solid-phase sorbent and its application for recognition clenbuterol from bovine urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2016; 1017-1018:18-27. DOI: 10.1016/j.jchromb.2016.02.019. View

14.

Dasenaki M, Thomaidis N . Multi-residue determination of 115 veterinary drugs and pharmaceutical residues in milk powder, butter, fish tissue and eggs using liquid chromatography-tandem mass spectrometry. Anal Chim Acta. 2015; 880:103-21. DOI: 10.1016/j.aca.2015.04.013. View

15.

Chen L, Wang X, Lu W, Wu X, Li J . Molecular imprinting: perspectives and applications. Chem Soc Rev. 2016; 45(8):2137-211. DOI: 10.1039/c6cs00061d. View

16.

Zhao Y, Zhou L, Pan S, Zhan P, Chen X, Jin M . Fast determination of 22 sulfonamides from chicken breast muscle using core-shell nanoring amino-functionalized superparamagnetic molecularly imprinted polymer followed by liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2014; 1345:17-28. DOI: 10.1016/j.chroma.2014.04.028. View

17.

Herrera-Herrera A, Hernandez-Borges J, Afonso M, Palenzuela J, Rodriguez-Delgado M . Comparison between magnetic and non magnetic multi-walled carbon nanotubes-dispersive solid-phase extraction combined with ultra-high performance liquid chromatography for the determination of sulfonamide antibiotics in water samples. Talanta. 2013; 116:695-703. DOI: 10.1016/j.talanta.2013.07.060. View

18.

Hu Y, Li Y, Liu R, Tan W, Li G . Magnetic molecularly imprinted polymer beads prepared by microwave heating for selective enrichment of β-agonists in pork and pig liver samples. Talanta. 2011; 84(2):462-70. DOI: 10.1016/j.talanta.2011.01.045. View

19.

Liu H, Lin S, Fuh M . Determination of chloramphenicol, thiamphenicol and florfenicol in milk and honey using modified QuEChERS extraction coupled with polymeric monolith-based capillary liquid chromatography tandem mass spectrometry. Talanta. 2016; 150:233-9. DOI: 10.1016/j.talanta.2015.12.045. View

20.

Zhao Z, Zhang Y, Xuan Y, Song W, Si W, Zhao Z . Ion-exchange solid-phase extraction combined with liquid chromatography-tandem mass spectrometry for the determination of veterinary drugs in organic fertilizers. J Chromatogr B Analyt Technol Biomed Life Sci. 2016; 1022:281-289. DOI: 10.1016/j.jchromb.2016.04.008. View