» Articles » PMID: 29171820

Acute Graft-versus-Host Disease - Biologic Process, Prevention, and Therapy

Overview
Journal N Engl J Med
Specialty General Medicine
Date 2017 Nov 25
PMID 29171820
Citations 564
Authors
Affiliations
Soon will be listed here.
Citing Articles

Whole-Blood Longitudinal Molecular Profiling Maps the Road of Graft Versus Host Disease (GVHD).

Bar M, El Anbari M, Rinchai D, Toufiq M, Kizhakayil D, Manjunath H Cancers (Basel). 2025; 17(5).

PMID: 40075650 PMC: 11899482. DOI: 10.3390/cancers17050802.


Macrophages in graft-versus-host disease (GVHD): dual roles as therapeutic tools and targets.

Raoufi A, Soleimani Samarkhazan H, Nouri S, Khaksari M, Abbasi Sourki P, Sargazi Aval O Clin Exp Med. 2025; 25(1):73.

PMID: 40048037 PMC: 11885342. DOI: 10.1007/s10238-025-01588-0.


Free fatty acid receptor-4 regulates T-cell-mediated allogeneic reaction through activating an aryl hydrocarbon receptor pathway.

Duah M, Zheng F, Shen J, Xu Y, Cao S, Yan Z Acta Pharm Sin B. 2025; 15(1):224-238.

PMID: 40041898 PMC: 11873605. DOI: 10.1016/j.apsb.2024.12.011.


NFAT single-deficient murine T cells reduce the risk of aGvHD while controlling cytomegalovirus infection.

Hundhausen N, Majumder S, Xiao Y, Haeusl S, Goehler H, Seal R iScience. 2025; 28(2):111937.

PMID: 40028277 PMC: 11872454. DOI: 10.1016/j.isci.2025.111937.


Improving bench-to-bedside translation for acute graft-versus-host disease models.

McDaniel Mims B, Furr K, Enriquez J, Grisham M Dis Model Mech. 2025; 18(2).

PMID: 40019007 PMC: 11892683. DOI: 10.1242/dmm.052084.


References
1.
Saha A, OConnor R, Thangavelu G, Lovitch S, Dandamudi D, Wilson C . Programmed death ligand-1 expression on donor T cells drives graft-versus-host disease lethality. J Clin Invest. 2016; 126(7):2642-60. PMC: 4922691. DOI: 10.1172/JCI85796. View

2.
Toubai T, Hou G, Mathewson N, Liu C, Wang Y, Oravecz-Wilson K . Siglec-G-CD24 axis controls the severity of graft-versus-host disease in mice. Blood. 2014; 123(22):3512-23. PMC: 4041170. DOI: 10.1182/blood-2013-12-545335. View

3.
Jankovic D, Ganesan J, Bscheider M, Stickel N, Weber F, Guarda G . The Nlrp3 inflammasome regulates acute graft-versus-host disease. J Exp Med. 2013; 210(10):1899-910. PMC: 3782050. DOI: 10.1084/jem.20130084. View

4.
Furlan S, Watkins B, Tkachev V, Flynn R, Cooley S, Ramakrishnan S . Transcriptome analysis of GVHD reveals aurora kinase A as a targetable pathway for disease prevention. Sci Transl Med. 2015; 7(315):315ra191. PMC: 4876606. DOI: 10.1126/scitranslmed.aad3231. View

5.
Jasperson L, Bucher C, Panoskaltsis-Mortari A, Mellor A, Munn D, Blazar B . Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality. Blood. 2009; 114(24):5062-70. PMC: 2788979. DOI: 10.1182/blood-2009-06-227587. View