SnapShot: Functions of Endoplasmic Reticulum Membrane Contact Sites

Overview

Journal Cell

Publisher Cell Press

Specialty Cell Biology

Date 2017 Nov 18

PMID 29149609

Citations 23

Authors

Raquel Salvador-Gallego

Melissa J Hoyer

Gia K Voeltz

Affiliations

Soon will be listed here.

Abstract

The endoplasmic reticulum (ER) consists of the nuclear envelope and a reticulated interconnected network of tubules and sheets. ER sheets are studded with ribosomes and provide the entryway for proteins into the secretory pathway. ER tubules move dynamically on microtubules and form membrane contact sites with other organelles, where membranes are tethered, but not fused. This Snapshot reviews key biological processes that take place at ER contact sites with the Golgi, endosomes, and mitochondria.

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