Chromosomal Assignment of a Glutamic Acid Transfer RNA (tRNAGlu) Gene to 1p36

Overview

Journal Hum Genet

Specialty Genetics

Date 1989 Jan 1

PMID 2912885

Citations 10

Authors

E Boyd

A Theriault

J P Goddard

M Kalaitsidaki

D H Spathas

J M Connor

Affiliations

Soon will be listed here.

Abstract

A gene for tRNAGlu has been assigned to human chromosome 1p36 by in situ hybridisation using a [3H]-labelled or biotinylated 2.4-kb (human) DNA fragment containing a tRNAGlu gene as a probe. With the biotinylated DNA probe a secondary statistically significant site of hybridisation was observed at 1q21-22 which might represent a pseudogene or related sequence. In fibroblasts from gorilla (Gorilla gorilla) using biotin labelling, a single site of hybridisation occurred at 1qter which provides further support for homology of 1q in the higher apes and human 1p.

Citing Articles

Regional chromosomal assignment of the Kell blood group locus (KEL) to chromosome 7q33-q35 by fluorescence in situ hybridization: evidence for the polypeptide nature of antigenic variation.

Murphy M, Morrison N, Miles J, Fraser R, Spurr N, Boyd E Hum Genet. 1993; 91(6):585-8.

PMID: 8340113 DOI: 10.1007/BF00205085.

Assignment of the gene encoding the human thyrotropin-releasing hormone receptor to 8q23 by fluorescence in situ hybridization.

Morrison N, Duthie S, Boyd E, Eidne K, Connor J Hum Genet. 1994; 93(6):716-8.

PMID: 8005602 DOI: 10.1007/BF00201580.

Assignment of the gene encoding the human gonadotropin-releasing hormone receptor to 4q13.2-13.3 by fluorescence in situ hybridization.

Morrison N, Sellar R, Boyd E, Eidne K, Connor J Hum Genet. 1994; 93(6):714-5.

PMID: 8005601 DOI: 10.1007/BF00201579.

Regional chromosomal assignment of the human glucocorticoid receptor gene to 5q31.

Theriault A, Boyd E, Harrap S, Hollenberg S, Connor J Hum Genet. 1989; 83(3):289-91.

PMID: 2793174 DOI: 10.1007/BF00285175.

Regional assignment of the human C1-inhibitor gene to 11q11-q13.1.

Theriault A, Whaley K, McPhaden A, Boyd E, Connor J Hum Genet. 1990; 84(5):477-9.

PMID: 2323781 DOI: 10.1007/BF00195824.

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