Analysis of the Conformations of the HIV-1 Protease from a Large Crystallographic Data Set

Overview

Journal Data Brief

Date 2017 Nov 11

PMID 29124093

Citations 5

Authors

Luigi Leonardo Palese

Affiliations

Soon will be listed here.

Abstract

The HIV-1 protease performs essential roles in viral maturation by processing specific cleavage sites in the Gag and Gag-Pol precursor polyproteins to release their mature forms. Here the analysis of a large HIV-1 protease data set (containing 552 dimer structures) are reported. These data are related to article entitled "Conformations of the HIV-1 protease: a crystal structure data set analysis" (Palese, 2017) [1].

Citing Articles

AI-Aided Search for New HIV-1 Protease Ligands.

Arrigoni R, Santacroce L, Ballini A, Palese L Biomolecules. 2023; 13(5).

PMID: 37238727 PMC: 10216636. DOI: 10.3390/biom13050858.

SARS-CoV-2 Main Protease Active Site Ligands in the Human Metabolome.

Sardanelli A, Isgro C, Palese L Molecules. 2021; 26(5).

PMID: 33807773 PMC: 7961382. DOI: 10.3390/molecules26051409.

Systematic Search for SARS-CoV-2 Main Protease Inhibitors for Drug Repurposing: Ethacrynic Acid as a Potential Drug.

Isgro C, Sardanelli A, Palese L Viruses. 2021; 13(1).

PMID: 33451132 PMC: 7828626. DOI: 10.3390/v13010106.

A New Look at the Structures of Old Sepsis Actors by Exploratory Data Analysis Tools.

Gnoni A, De Nitto E, Scacco S, Santacroce L, Palese L Antibiotics (Basel). 2019; 8(4).

PMID: 31739644 PMC: 6963771. DOI: 10.3390/antibiotics8040225.

Translational control mechanisms in cutaneous malignant melanoma: the role of eIF2α.

Maida I, Zanna P, Guida S, Ferretta A, Cocco T, Palese L J Transl Med. 2019; 17(1):20.

PMID: 30634982 PMC: 6329103. DOI: 10.1186/s12967-019-1772-z.

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