Nodal Involvement in Oral Squamous Cell Carcinoma (SCC) Patients with and Without Oral Sub Mucous Fibrosis (OSMF): A Comparative Study

Overview

Journal J Oral Biol Craniofac Res

Publisher Elsevier

Date 2017 Nov 11

PMID 29123995

Citations 3

Authors

Gaurav Singh

Amar Singh Rana

Anshuman Kumar

Ashish Prajapati

Shubham Kumar

Parul Singh

Affiliations

Soon will be listed here.

Abstract

Aim: The aim of the study is to compare and evaluate neck node status of oral cancer patients with and without Oral Sub Mucous Fibrosis (OSMF) treated surgically.

Methodology: A total of 50 patients of Indian origin who were diagnosed with Squamous Cell Carcinoma (SCC) of oral cavity and had not taken any prior treatment were included in the study. Clinical examination and metastatic workup was done for all patients. Patients diagnosed with resectable primary and without distant metastasis were taken up for surgery. For all patients, resected specimens were sent for radical histopathological examination.

Result: The differences in nodal involvement in T, T & T sized lesions were non-significant, while in T sized lesions, a statistically significant lower incidence of nodal involvement in patients with-OSMF as compared to patients without OSMF was observed.

Conclusion: Presence of N neck in T lesions in oral SCC patients with OSMF has potential implications on the present pattern of spread and treatment protocols, leading to need for further research with OSMF as independent risk factor for nodal involvement.

Citing Articles

Unexpected additional pathologies at the surgical margins of oral squamous cell carcinoma.

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A retrospective study of clinicopathological features of oral squamous cell carcinoma with and without oral submucous fibrosis.

Acharya S, Rahman S, Hallikeri K J Oral Maxillofac Pathol. 2019; 23(1):162.

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An Evaluation of Clinical and Histopathological Aspects of Patients with Oral Submucous Fibrosis in the Background of Oral Squamous Cell Carcinoma.

Siriwardena B, Jayawardena K, Senarath N, Tilakaratne W Biomed Res Int. 2018; 2018:4154165.

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