Screening for the Presence of Mcr-1/mcr-2 Genes in Shiga Toxin-producing Escherichia Coli Recovered from a Major Produce-production Region in California

Overview

Journal PLoS One

Specialties General Medicine
Science

Date 2017 Nov 9

PMID 29117270

Citations 4

Authors

Daniela Mavrici

Jaszemyn C Yambao

Bertram G Lee

Beatriz Quinones

Xiaohua He

Affiliations

Soon will be listed here.

Abstract

The rapid spreading of polymyxin E (colistin) resistance among bacterial strains through the horizontally transmissible mcr-1 and mcr-2 plasmids has become a serious concern. The emergence of these genes in Shiga toxin-producing Escherichia coli (STEC), a group of human pathogenic bacteria was even more worrisome, urging us to investigate the prevalence of mcr genes among STEC isolates. A total of 1000 STEC isolates, recovered from livestock, wildlife, produce and other environmental sources in a major production region for leafy vegetables in California during 2006-2014, were screened by PCR for the presence of plasmid-borne mcr-1 and mcr-2. All isolates tested yielded negative results, indicating if any, the occurrence rate of mcr-1/mcr-2 among STEC was very low in this agricultural region. This study provides valuable information such as sample size needed and methodologies for future surveillance programs of antimicrobial resistance.

Citing Articles

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