» Articles » PMID: 29103270

Analysis of Lethality in Echinococcal Disease

Overview
Specialty Parasitology
Date 2017 Nov 7
PMID 29103270
Citations 5
Authors
Affiliations
Soon will be listed here.
Abstract

The information on mortality from echinococcosis is important not only for a better understanding of the severity of the disease, but also for evaluating the effectiveness of public health interventions. The aim of this research was to study the causes of mortality from echinococcosis. We have collected and analyzed the materials of 1,470 patients in 10 age - groups in the Republic of Armenia (from 2000 to 2016). To find out the causes of mortality from echinococcosis, we have analyzed the medical histories and protocols of postmortem examinations of 19 deaths from echinococcosis and 17 deaths due to other indirect causes not associated with the parasite. The average annual death rate from echinococcosis is 0.007 per 10,000 population, and the mortality is 1.29 (per 100 patients). The highest mortality occurs in people aged 70-79. Mortality from echinococcosis is also recorded among the unoperated children. The rupture of the parasitic cyst and hepatic insufficiency are major among the direct causes of mortality. Sometimes the hydatid cysts unrecognized during the life were first diagnosed at autopsy. Insufficient qualification of doctors in the field of helminthology, as well as the latent course of the disease or manifestation of minor symptoms in echinococcosis over a long period often led to medical errors. Further decline in mortality can be achieved by early diagnosis, timely hospitalization and treatment before the development of severe complications worsening the prognosis and outcomes of surgical intervention.

Citing Articles

Complicated Liver Cystic Echinococcosis-A Comprehensive Literature Review and a Tale of Two Extreme Cases.

Calu V, Enciu O, Toma E, Parvuletu R, Piriianu D, Miron A Tomography. 2024; 10(6):922-934.

PMID: 38921947 PMC: 11209078. DOI: 10.3390/tomography10060070.


α-Mangostin Exhibits a Therapeutic Effect on Spinal Cystic Echinococcosis by Affecting Glutamine Metabolism.

Wang S, Sun H, Wang S, Ren Q, Dai Y, Zhu M Antimicrob Agents Chemother. 2023; 67(6):e0009823.

PMID: 37140388 PMC: 10269084. DOI: 10.1128/aac.00098-23.


Endoscopic Endonasal Surgery for a Pterygopalatine Fossa Hydatid Cyst.

Peterkovic V, Marjanovic Kavanagh M, Baric H, Njiric N, Balen-Topic M, Beck R J Maxillofac Oral Surg. 2022; 21(1):93-98.

PMID: 35400908 PMC: 8934795. DOI: 10.1007/s12663-021-01545-w.


A Pilot Comparative Study Between Serological and Genetic Investigations in Relationship to Clinical Outcomes on Patients with Cystic Echinococcosis.

Altintas N, Karamil S, Turkum O, Akil M, Sakarya A, Bozkaya H Helminthologia. 2020; 57(2):91-99.

PMID: 32518485 PMC: 7261030. DOI: 10.2478/helm-2020-0012.


Study on the effect of an ion channel inhibitor "Fluralaner" on protoscolices and metacestode layers in vitro.

Zahran F, Ezz El-Din H, Shehata M J Parasit Dis. 2020; 44(2):411-419.

PMID: 32508416 PMC: 7244642. DOI: 10.1007/s12639-020-01224-6.

References
1.
Qadri S, Hamdani N, Bhat A, Lone M . Unusual presentation of an intraventricular hydatid cyst as a bleeding cystic tumor: A case report and brief review. Asian J Neurosurg. 2017; 12(2):324-327. PMC: 5409402. DOI: 10.4103/1793-5482.145541. View

2.
Belhassen-Garcia M, Romero-Alegria A, Velasco-Tirado V, Alonso-Sardon M, Lopez-Bernus A, Alvela-Suarez L . Study of hydatidosis-attributed mortality in endemic area. PLoS One. 2014; 9(3):e91342. PMC: 3954695. DOI: 10.1371/journal.pone.0091342. View

3.
Kern P, Menezes da Silva A, Akhan O, Mullhaupt B, Vizcaychipi K, Budke C . The Echinococcoses: Diagnosis, Clinical Management and Burden of Disease. Adv Parasitol. 2017; 96:259-369. DOI: 10.1016/bs.apar.2016.09.006. View

4.
Sarkar S, Roy H, Saha P, Sengupta M, Sarder K, Sengupta M . Cystic echinococcosis: A neglected disease at usual and unusual locations. Trop Parasitol. 2017; 7(1):51-55. PMC: 5369277. DOI: 10.4103/tp.TP_55_16. View

5.
Hosseini M, Hedjazi A, Bahrami R . Sudden death due to anaphylactic shock in a patient with an intact hepatic hydatid cyst. Am J Forensic Med Pathol. 2014; 35(4):256-7. DOI: 10.1097/PAF.0000000000000128. View