Gastrointestinal Involvement in Systemic Sclerosis: An Update

Overview

Journal J Clin Rheumatol

Date 2017 Nov 3

PMID 29095721

Citations 28

Authors

John B Miller

Nisarg Gandhi

John Clarke

Zsuzsanna McMahan

Affiliations

Soon will be listed here.

Citing Articles

Prevalence of Gastroesophageal Reflux in Interstitial Lung Diseases Clinic.

Akhter N, Sumalani K, Chawla D, Rizvi N Cureus. 2025; 16(12):e76454.

PMID: 39866988 PMC: 11769694. DOI: 10.7759/cureus.76454.

Evidence for targeting autonomic dysfunction in systemic sclerosis: A scoping review.

Cuevas S, Mayer E, Hughes M, Adler B, McMahan Z J Scleroderma Relat Disord. 2025; 23971983241308050.

PMID: 39790996 PMC: 11707778. DOI: 10.1177/23971983241308050.

Mirtazapine Therapy for a Patient With Weight Loss and Gastroparesis Associated With Limited Systemic Sclerosis.

Jagadish A, Notta S, Falasca G J Pharm Technol. 2024; 40(4):207-209.

PMID: 39157639 PMC: 11325680. DOI: 10.1177/87551225241250282.

in gastrointestinal manifestation of systemic sclerosis.

Raja J, Muthusamy S, Ng C, Mahadeva S J Scleroderma Relat Disord. 2024; 9(2):117-123.

PMID: 38910603 PMC: 11188847. DOI: 10.1177/23971983241227133.

Prevalence and risk factors for medication-refractory reflux esophagitis in patients with systemic sclerosis in Japan.

Kuribayashi S, Nakamura F, Motegi S, Hara K, Hosaka H, Sekiguchi A J Gastroenterol. 2024; 59(3):179-186.

PMID: 38252140 DOI: 10.1007/s00535-024-02076-0.

References

Stolte M, Meining A, Seifert E, Alexandridis T . Treatment with lansoprazole also induces hypertrophy of the parietal cells of the stomach. Pathol Res Pract. 2000; 196(1):9-13. View

Roberts C, Hummers L, Ravich W, Wigley F, Hutchins G . A case-control study of the pathology of oesophageal disease in systemic sclerosis (scleroderma). Gut. 2006; 55(12):1697-703. PMC: 1856462. DOI: 10.1136/gut.2005.086074. View

Karamanolis G, Tack J . Promotility medications--now and in the future. Dig Dis. 2006; 24(3-4):297-307. DOI: 10.1159/000092883. View

Thonhofer R, Siegel C, Trummer M, Graninger W . Early endoscopy in systemic sclerosis without gastrointestinal symptoms. Rheumatol Int. 2010; 32(1):165-8. DOI: 10.1007/s00296-010-1595-y. View

Simren M, Stotzer P . Use and abuse of hydrogen breath tests. Gut. 2006; 55(3):297-303. PMC: 1856094. DOI: 10.1136/gut.2005.075127. View

Ganzini L, Casey D, Hoffman W, McCall A . The prevalence of metoclopramide-induced tardive dyskinesia and acute extrapyramidal movement disorders. Arch Intern Med. 1993; 153(12):1469-75. View

Taroni J, Martyanov V, Huang C, Mahoney J, Hirano I, Shetuni B . Molecular characterization of systemic sclerosis esophageal pathology identifies inflammatory and proliferative signatures. Arthritis Res Ther. 2015; 17:194. PMC: 4518531. DOI: 10.1186/s13075-015-0695-1. View

Rees W, Leigh R, Christofides N, Bloom S, Turnberg L . Interdigestive motor activity in patients with systemic sclerosis. Gastroenterology. 1982; 83(3):575-80. View

Naylor W, Douglass C, Mix E . The nonsurgical treatment of microstomia in scleroderma: a pilot study. Oral Surg Oral Med Oral Pathol. 1984; 57(5):508-11. DOI: 10.1016/0030-4220(84)90309-8. View

10.

Steen V, Domsic R, Lucas M, Fertig N, Medsger Jr T . A clinical and serologic comparison of African American and Caucasian patients with systemic sclerosis. Arthritis Rheum. 2012; 64(9):2986-94. PMC: 3557827. DOI: 10.1002/art.34482. View

11.

Attar A, Flourie B, Rambaud J, Franchisseur C, Ruszniewski P, Bouhnik Y . Antibiotic efficacy in small intestinal bacterial overgrowth-related chronic diarrhea: a crossover, randomized trial. Gastroenterology. 1999; 117(4):794-7. DOI: 10.1016/s0016-5085(99)70336-7. View

12.

Nietert P, Mitchell H, Bolster M, Curran M, Tilley B, Silver R . Correlates of depression, including overall and gastrointestinal functional status, among patients with systemic sclerosis. J Rheumatol. 2005; 32(1):51-7. View

13.

Frech T, Khanna D, Maranian P, Frech E, Sawitzke A, Murtaugh M . Probiotics for the treatment of systemic sclerosis-associated gastrointestinal bloating/ distention. Clin Exp Rheumatol. 2011; 29(2 Suppl 65):S22-5. View

14.

Davis R, Clench M, Mathias J . Effects of domperidone in patients with chronic unexplained upper gastrointestinal symptoms: a double-blind, placebo-controlled study. Dig Dis Sci. 1988; 33(12):1505-11. DOI: 10.1007/BF01535938. View

15.

Atkinson M, Summerling M . Oesophageal changes in systemic sclerosis. Gut. 1966; 7(4):402-8. PMC: 1552419. DOI: 10.1136/gut.7.4.402. View

16.

Ibanez G, Alarcon-Segovia D . Stimulatory effect of metoclopramide on the esophagus and lower esophageal sphincter of patients of patients with PSS. Arthritis Rheum. 1977; 20(1):30-4. DOI: 10.1002/art.1780200105. View

17.

Foocharoen C, Chunlertrith K, Mairiang P, Mahakkanukrauh A, Suwannaroj S, Namvijit S . Effectiveness of add-on therapy with domperidone vs alginic acid in proton pump inhibitor partial response gastro-oesophageal reflux disease in systemic sclerosis: randomized placebo-controlled trial. Rheumatology (Oxford). 2016; 56(2):214-222. DOI: 10.1093/rheumatology/kew216. View

18.

Ghoos Y, Maes B, Geypens B, Mys G, Hiele M, Rutgeerts P . Measurement of gastric emptying rate of solids by means of a carbon-labeled octanoic acid breath test. Gastroenterology. 1993; 104(6):1640-7. DOI: 10.1016/0016-5085(93)90640-x. View

19.

Corazza G, Biagi F, ALBANO O, Bianchi Porro G, CHELI R, Mazzacca G . Levosulpiride in functional dyspepsia: a multicentric, double-blind, controlled trial. Ital J Gastroenterol. 1996; 28(6):317-23. View

20.

Deane A, Wong G, Horowitz M, Zaknic A, Summers M, Di Bartolomeo A . Randomized double-blind crossover study to determine the effects of erythromycin on small intestinal nutrient absorption and transit in the critically ill. Am J Clin Nutr. 2012; 95(6):1396-402. DOI: 10.3945/ajcn.112.035691. View