Clinical Characteristics of Localized Aggressive Periodontitis in Primary Dentition

Overview

Journal J Clin Pediatr Dent

Specialties Dentistry
Pediatrics

Date 2017 Nov 1

PMID 29087795

Citations 10

Authors

Karina Miller

Tina Treloar

Marcio Guelmann

Wellington J Rody Jr

Luciana M Shaddox

Affiliations

Soon will be listed here.

Abstract

Objectives: Due to the low prevalence of localized aggressive periodontitis (LAP), clinical characteristics of LAP in primary dentition are derived from a few case reports/series in the literature. The goal of this study was to determine common clinical characteristics such as bone and root resorption patterns, in a series of cases with LAP in primary dentition. We hypothesize these cases present aggressive periodontal bone destruction starting mostly around first primary molars and atypical root resorption patterns.

Study Design: We have evaluated 33 LAP cases in primary dentition for pattern of bone destruction, root resorption and early exfoliation.

Results: Cases evaluated were aged 5-12 (mean=8.7 years). Thirty cases presented more severe bone loss on first than second molars, with relatively fast progression to second molars, altered pattern of root resorption, mostly external (n=16) and early exfoliation of primary teeth due to periodontal bone loss, rather than physiologic root resorption (n=11).

Conclusions: This study showed common clinical characteristics found in LAP in primary molars, including possible initiation on first primary molars and abnormal root resorption patterns. These characteristics are important to be early identified and treated in order to prevent possible progression into the permanent dentition.

Citing Articles

Periodontal diseases in Down syndrome during childhood: a scoping review.

Vergier V, Collignon A, Gosset M, Bonnet A BMC Oral Health. 2025; 25(1):161.

PMID: 39885472 PMC: 11783834. DOI: 10.1186/s12903-025-05540-2.

Grade C Molar-Incisor Pattern Periodontitis in Young Adults: What Have We Learned So Far?.

Miguel M, Shaddox L Pathogens. 2024; 13(7).

PMID: 39057807 PMC: 11279578. DOI: 10.3390/pathogens13070580.

Periodontal inflammatory and microbial profiles in healthy young African Americans and Caucasians.

Sabbagh S, Adatorwovor R, Kirakodu S, Rojas-Ramirez M, Al-Sabbagh M, Dawson D J Clin Periodontol. 2024; 51(7):895-904.

PMID: 38763508 PMC: 11182714. DOI: 10.1111/jcpe.13989.

Evaluation of microbiome in primary and permanent dentition in grade C periodontitis in young individuals.

Koo S, Fernandes J, Li L, Huang H, Aukhil I, Harrison P J Periodontol. 2024; 95(7):650-661.

PMID: 38476115 PMC: 11265979. DOI: 10.1002/JPER.23-0504.

Treatment of Periodontitis Affecting Human Primary Teeth-A Systematic Review.

Guha Biswas P, Mohan A, Kandaswamy E Dent J (Basel). 2023; 11(7).

PMID: 37504237 PMC: 10378644. DOI: 10.3390/dj11070171.

References

Melnick M, Shields E, Bixler D . Periodontosis: a phenotypic and genetic analysis. Oral Surg Oral Med Oral Pathol. 1976; 42(1):32-41. DOI: 10.1016/0030-4220(76)90029-3. View

Kamat M, Puranik R, Vanaki S, Kamat S . An insight into the regulatory mechanisms of cells involved in resorption of dental hard tissues. J Oral Maxillofac Pathol. 2013; 17(2):228-33. PMC: 3830232. DOI: 10.4103/0973-029X.119736. View

BAER P . The case for periodontosis as a clinical entity. J Periodontol. 1971; 42(8):516-20. DOI: 10.1902/jop.1971.42.8.516. View

Harokopakis-Hajishengallis E . Physiologic root resorption in primary teeth: molecular and histological events. J Oral Sci. 2007; 49(1):1-12. DOI: 10.2334/josnusd.49.1. View

Bartold P, Van Dyke T . Periodontitis: a host-mediated disruption of microbial homeostasis. Unlearning learned concepts. Periodontol 2000. 2013; 62(1):203-17. PMC: 3692012. DOI: 10.1111/j.1600-0757.2012.00450.x. View

Hammarstrom L, Lindskog S . General morphological aspects of resorption of teeth and alveolar bone. Int Endod J. 1985; 18(2):93-108. DOI: 10.1111/j.1365-2591.1985.tb00426.x. View

Page R, Bowen T, Altman L, Vandesteen E, Ochs H, Mackenzie P . Prepubertal periodontitis. I. Definition of a clinical disease entity. J Periodontol. 1983; 54(5):257-71. DOI: 10.1902/jop.1983.54.5.257. View

Nakagawa S, Fujii H, Machida Y, Okuda K . A longitudinal study from prepuberty to puberty of gingivitis. Correlation between the occurrence of Prevotella intermedia and sex hormones. J Clin Periodontol. 1994; 21(10):658-65. DOI: 10.1111/j.1600-051x.1994.tb00783.x. View

Fuss Z, Tsesis I, Lin S . Root resorption--diagnosis, classification and treatment choices based on stimulation factors. Dent Traumatol. 2003; 19(4):175-82. DOI: 10.1034/j.1600-9657.2003.00192.x. View

10.

Baab D, Page R, Morton T . Studies of a family manifesting premature exfoliation of deciduous teeth. J Periodontol. 1985; 56(7):403-9. DOI: 10.1902/jop.1985.56.7.403. View

11.

Lunt R, LAW D . A review of the chronology of eruption of deciduous teeth. J Am Dent Assoc. 1974; 89(4):872-9. DOI: 10.14219/jada.archive.1974.0484. View

12.

Uchiyama M, Nakamichi Y, Nakamura M, Kinugawa S, Yamada H, Udagawa N . Dental pulp and periodontal ligament cells support osteoclastic differentiation. J Dent Res. 2009; 88(7):609-14. DOI: 10.1177/0022034509340008. View

13.

Sasaki T . Differentiation and functions of osteoclasts and odontoclasts in mineralized tissue resorption. Microsc Res Tech. 2003; 61(6):483-95. DOI: 10.1002/jemt.10370. View

14.

Boraz R . Prepubertal periodontitis: report of a generalized case involving the primary dentition. J Pedod. 1985; 9(2):165-8. View

15.

Raber-Durlacher J, van Steenbergen T, Van der Velden U, de Graaff J, Abraham-Inpijn L . Experimental gingivitis during pregnancy and post-partum: clinical, endocrinological, and microbiological aspects. J Clin Periodontol. 1994; 21(8):549-58. DOI: 10.1111/j.1600-051x.1994.tb01172.x. View

16.

Susin C, Haas A, Albandar J . Epidemiology and demographics of aggressive periodontitis. Periodontol 2000. 2014; 65(1):27-45. DOI: 10.1111/prd.12019. View

17.

Sjodin B, Crossner C, Unell L, Ostlund P . A retrospective radiographic study of alveolar bone loss in the primary dentition in patients with localized juvenile periodontitis. J Clin Periodontol. 1989; 16(2):124-7. DOI: 10.1111/j.1600-051x.1989.tb01625.x. View

18.

FOUREL J . Periodontosis: a periodontal syndrome. J Periodontol. 1972; 43(4):240-55. DOI: 10.1902/jop.1972.43.4.240. View

19.

Nasehi A, Mazhari F, Mohtasham N . Localized idiopathic root resorption in the primary dentition: Review of the literature and a case report. Eur J Dent. 2016; 9(4):603-609. PMC: 4745246. DOI: 10.4103/1305-7456.172617. View

20.

Bimstein E . Seven-year follow-up of 10 children with periodontitis. Pediatr Dent. 2003; 25(4):389-96. View