Maternal Nutritional Deficiencies and Small-for-Gestational-Age Neonates at Birth of Women Who Have Undergone Bariatric Surgery

Overview

Journal J Pregnancy

Publisher Wiley

Specialty Gynecology & Obstetrics

Date 2017 Oct 31

PMID 29082043

Citations 24

Authors

J Hazart

D Le Guennec

M Accoceberry

D Lemery

A Mulliez

N Farigon

C Lahaye

M Miolanne-Debouit

Y Boirie

Affiliations

Soon will be listed here.

Abstract

The aim is to compare the prevalence of maternal deficiencies in micronutrients, the obstetrical and neonatal complications after bariatric surgery according to surgical techniques, the time between surgery and conception, and BMI at the onset of pregnancy. A retrospective cohort study concerned 57 singleton pregnancies between 2011 and 2016 of 48 adult women who have undergone bariatric surgery. Small-for-gestational-age neonates were identified in 36.0% of pregnancies. With supplements intake (periconceptional period: 56.8%, trimester 1 (T1): 77.8%, T2: 96.3%, and T3: 100.0%), nutritional deficiencies involved vitamins A (T1: 36.4%, T2: 21.1%, and T3: 40.0%), D (T1: 33.3%, T2: 26.3%, and T3: 8.3%), C (T1: 66.7%, T2: 41.2%, and T3: 83.3%), B1 (T1: 45.5%, T2: 15.4%, and T3: 20.0%), and B9 (T1: 14.3%, T2: 0%, and T3: 9.1%) and selenium (T1: 77.8%, T2: 22.2%, and T3: 50.0%). There was no significant difference in the prevalence of nutritional deficiencies and complications according to surgery procedures and in the prevalence of pregnancy issues according to BMI at the beginning of the pregnancy and time between surgery and pregnancy. Prevalence of micronutritional deficiencies and small-for-gestational-age neonates is high in pregnant women following bariatric surgery. Specific nutritional programmes should be recommended for these women.

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References

Poitou Bernert C, Ciangura C, Coupaye M, Czernichow S, Bouillot J, Basdevant A . Nutritional deficiency after gastric bypass: diagnosis, prevention and treatment. Diabetes Metab. 2007; 33(1):13-24. DOI: 10.1016/j.diabet.2006.11.004. View

Berlac J, Skovlund C, Lidegaard O . Obstetrical and neonatal outcomes in women following gastric bypass: a Danish national cohort study. Acta Obstet Gynecol Scand. 2014; 93(5):447-53. DOI: 10.1111/aogs.12368. View

. ACOG practice bulletin no. 105: bariatric surgery and pregnancy. Obstet Gynecol. 2009; 113(6):1405-1413. DOI: 10.1097/AOG.0b013e3181ac0544. View

Ducarme G, Revaux A, Rodrigues A, Aissaoui F, Pharisien I, Uzan M . Obstetric outcome following laparoscopic adjustable gastric banding. Int J Gynaecol Obstet. 2007; 98(3):244-7. DOI: 10.1016/j.ijgo.2007.02.020. View

Dao T, Kuhn J, Ehmer D, Fisher T, McCarty T . Pregnancy outcomes after gastric-bypass surgery. Am J Surg. 2006; 192(6):762-6. DOI: 10.1016/j.amjsurg.2006.08.041. View

Jans G, Matthys C, Bogaerts A, Lannoo M, Verhaeghe J, Van der Schueren B . Maternal micronutrient deficiencies and related adverse neonatal outcomes after bariatric surgery: a systematic review. Adv Nutr. 2015; 6(4):420-9. PMC: 4496736. DOI: 10.3945/an.114.008086. View

Chevrot A, Kayem G, Coupaye M, Lesage N, Msika S, Mandelbrot L . Impact of bariatric surgery on fetal growth restriction: experience of a perinatal and bariatric surgery center. Am J Obstet Gynecol. 2015; 214(5):655.e1-7. DOI: 10.1016/j.ajog.2015.11.017. View

Pelizzo G, Calcaterra V, Fusillo M, Nakib G, Ierullo A, Alfei A . Malnutrition in pregnancy following bariatric surgery: three clinical cases of fetal neural defects. Nutr J. 2014; 13:59. PMC: 4071151. DOI: 10.1186/1475-2891-13-59. View

Fumery L, Pigeyre M, Fournier C, Arnalsteen L, Rivaux G, Subtil D . [Impact of bariatric surgery on obstetric prognosis]. Gynecol Obstet Fertil. 2012; 41(3):156-63. DOI: 10.1016/j.gyobfe.2012.09.004. View

10.

Ciangura C, Nizard J, Poitou-Bernert C, Dommergues M, Oppert J, Basdevant A . [Pregnancy and bariatric surgery: Critical points]. J Gynecol Obstet Biol Reprod (Paris). 2015; 44(6):496-502. DOI: 10.1016/j.jgyn.2015.01.010. View

11.

Arterburn D, Olsen M, Smith V, Livingston E, Van Scoyoc L, Yancy Jr W . Association between bariatric surgery and long-term survival. JAMA. 2015; 313(1):62-70. DOI: 10.1001/jama.2014.16968. View

12.

Bellamy L, Casas J, Hingorani A, Williams D . Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis. Lancet. 2009; 373(9677):1773-9. DOI: 10.1016/S0140-6736(09)60731-5. View

13.

Jans G, Matthys C, Bel S, Ameye L, Lannoo M, Van der Schueren B . AURORA: bariatric surgery registration in women of reproductive age - a multicenter prospective cohort study. BMC Pregnancy Childbirth. 2016; 16(1):195. PMC: 4966861. DOI: 10.1186/s12884-016-0992-y. View

14.

Berti C, Decsi T, Dykes F, Hermoso M, Koletzko B, Massari M . Critical issues in setting micronutrient recommendations for pregnant women: an insight. Matern Child Nutr. 2012; 6 Suppl 2:5-22. PMC: 6860719. DOI: 10.1111/j.1740-8709.2010.00269.x. View

15.

Johansson K, Cnattingius S, Naslund I, Roos N, Trolle Lagerros Y, Granath F . Outcomes of pregnancy after bariatric surgery. N Engl J Med. 2015; 372(9):814-24. DOI: 10.1056/NEJMoa1405789. View

16.

Mandrup Kjaer M, Lauenborg J, Breum B, Nilas L . The risk of adverse pregnancy outcome after bariatric surgery: a nationwide register-based matched cohort study. Am J Obstet Gynecol. 2013; 208(6):464.e1-5. DOI: 10.1016/j.ajog.2013.02.046. View

17.

Ducarme G, Chesnoy V, Lemarie P, Koumare S, Krawczykowski D . Pregnancy outcomes after laparoscopic sleeve gastrectomy among obese patients. Int J Gynaecol Obstet. 2015; 130(2):127-31. DOI: 10.1016/j.ijgo.2015.03.022. View

18.

Haddow J, HILL L, Kloza E, Thanhauser D . Neural tube defects after gastric bypass. Lancet. 1986; 1(8493):1330. DOI: 10.1016/s0140-6736(86)91252-3. View

19.

Bischoff S, Boirie Y, Cederholm T, Chourdakis M, Cuerda C, Delzenne N . Towards a multidisciplinary approach to understand and manage obesity and related diseases. Clin Nutr. 2016; 36(4):917-938. DOI: 10.1016/j.clnu.2016.11.007. View

20.

Maggard M, Yermilov I, Li Z, Maglione M, Newberry S, Suttorp M . Pregnancy and fertility following bariatric surgery: a systematic review. JAMA. 2008; 300(19):2286-96. DOI: 10.1001/jama.2008.641. View