Shear Wave Elastography Evaluation in Pediatric Testicular Microlithiasis: a Comparative Study

Overview

Journal J Med Ultrason (2001)

Specialty Radiology

Date 2017 Oct 28

PMID 29075915

Citations 8

Authors

Zuhal Bayramoglu

Sedat Giray Kandemirli

Rana Gunoz Comert

Yunus Emre Akpinar

Emine Caliskan

Ravza Yilmaz

Tayfun Mevlut Oktar

Bilal Cetin

Mehmet Cingoz

Ibrahim Adaletli

Affiliations

Soon will be listed here.

Abstract

Purpose: The aim of this study was to evaluate the testicular parenchyma in pediatric patients with testicular microlithiasis by shear wave elastography (SWE) and compare the values with normal control subjects.

Methods: Twenty-three patients previously diagnosed with testicular microlithiasis under follow-up for 20 ± 11 months were included in the study group. In the control group, 31 patients with no medical history that could affect testicular tissue were prospectively included. Forty-six testes in the study group and 62 testes in the control group were evaluated with gray-scale ultrasound and SWE.

Results: There were no differences in age and testes volume between the study and control groups. The mean SWE values of all testes based on elasticity and speed parameters in the study group were 8.84 ± 2.86 kPa and 1.66 ± 0.26 m/s, respectively. In the control group, mean SWE values were 5.26 ± 1.17 kPa and 1.31 ± 0.14 m/s, respectively. Elasticity values were significantly higher in testes with microlithiasis as compared with the control group (p < 0.001).

Conclusions: SWE evaluation demonstrates the effects of ultrastructural changes in elasticity that are not detected on gray-scale ultrasound. SWE is a more reliable method in follow-up examinations for pediatric testicular microlithiasis.

Citing Articles

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References

Dede O, Teke M, Daggulli M, Utangac M, Bas O, Penbegul N . Elastography to assess the effect of varicoceles on testes: a prospective controlled study. Andrologia. 2015; 48(3):257-61. DOI: 10.1111/and.12440. View

Aigner F, De Zordo T, Pallwein-Prettner L, Junker D, Schafer G, Pichler R . Real-time sonoelastography for the evaluation of testicular lesions. Radiology. 2012; 263(2):584-9. DOI: 10.1148/radiol.12111732. View

Drut R, Drut R . Testicular microlithiasis: histologic and immunohistochemical findings in 11 pediatric cases. Pediatr Dev Pathol. 2002; 5(6):544-50. DOI: 10.1007/s10024-002-0015-z. View

Backus M, Mack L, Middleton W, King B, Winter 3rd T, True L . Testicular microlithiasis: imaging appearances and pathologic correlation. Radiology. 1994; 192(3):781-5. DOI: 10.1148/radiology.192.3.8058947. View

Bennett H, Middleton W, Bullock A, Teefey S . Testicular microlithiasis: US follow-up. Radiology. 2001; 218(2):359-63. DOI: 10.1148/radiology.218.2.r01fe25359. View

Kalyoncu Ucar A, Alis D, Samanci C, Aslan M, Arioz Habibi H, Dikici A . A preliminary study of shear wave elastography for the evaluation of unilateral palpable undescended testes. Eur J Radiol. 2016; 86:248-251. DOI: 10.1016/j.ejrad.2016.11.026. View

Goede J, Hack W, van der Voort-Doedens L, Sijstermans K, Pierik F . Prevalence of testicular microlithiasis in asymptomatic males 0 to 19 years old. J Urol. 2009; 182(4):1516-20. DOI: 10.1016/j.juro.2009.06.065. View

Magri F, Chytiris S, Capelli V, Alessi S, Nalon E, Rotondi M . Shear wave elastography in the diagnosis of thyroid nodules: feasibility in the case of coexistent chronic autoimmune Hashimoto's thyroiditis. Clin Endocrinol (Oxf). 2011; 76(1):137-41. DOI: 10.1111/j.1365-2265.2011.04170.x. View

Cast J, Nelson W, Early A, Biyani S, Cooksey G, Warnock N . Testicular microlithiasis: prevalence and tumor risk in a population referred for scrotal sonography. AJR Am J Roentgenol. 2000; 175(6):1703-6. DOI: 10.2214/ajr.175.6.1751703. View

10.

Marte A, Pintozzi L, Creti G, Lelli Chiesa P, Di Renzo D, Gasparella M . Long-Term Follow-Up of Testicular Microlithiasis in Children and Adolescents: Multicenter Prospective Cohort Study of the Italian Society of Pediatric Urology. Eur J Pediatr Surg. 2016; 27(2):155-160. DOI: 10.1055/s-0036-1572552. View

11.

Renshaw A . Testicular calcifications: incidence, histology and proposed pathological criteria for testicular microlithiasis. J Urol. 1998; 160(5):1625-8. DOI: 10.1016/s0022-5347(01)62364-4. View

12.

Cooper M, Kaefer M, Fan R, Rink R, Jennings S, Karmazyn B . Testicular microlithiasis in children and associated testicular cancer. Radiology. 2014; 270(3):857-63. DOI: 10.1148/radiol.13130394. View

13.

Sun Z, Xie M, Xiang F, Song Y, Yu C, Zhang Y . Utility of Real-Time Shear Wave Elastography in the Assessment of Testicular Torsion. PLoS One. 2015; 10(9):e0138523. PMC: 4575189. DOI: 10.1371/journal.pone.0138523. View

14.

Samir A, Allegretti A, Zhu Q, Dhyani M, Anvari A, Sullivan D . Shear wave elastography in chronic kidney disease: a pilot experience in native kidneys. BMC Nephrol. 2015; 16:119. PMC: 4521488. DOI: 10.1186/s12882-015-0120-7. View

15.

Goddi A, Sacchi A, Magistretti G, Almolla J, Salvadore M . Real-time tissue elastography for testicular lesion assessment. Eur Radiol. 2011; 22(4):721-30. PMC: 3297754. DOI: 10.1007/s00330-011-2312-2. View

16.

Winter T, Kim B, Lowrance W, Middleton W . Testicular Microlithiasis: What Should You Recommend?. AJR Am J Roentgenol. 2016; 206(6):1164-9. DOI: 10.2214/AJR.15.15226. View

17.

Shanmugasundaram R, Singh J, Kekre N . Testicular microlithiasis: Is there an agreed protocol?. Indian J Urol. 2009; 23(3):234-9. PMC: 2721596. DOI: 10.4103/0970-1591.33442. View

18.

Holm M, Lenz S, De Meyts E, Skakkebaek N . Microcalcifications and carcinoma in situ of the testis. BJU Int. 2001; 87(2):144-9. DOI: 10.1046/j.1464-410x.2001.00020.x. View

19.

Richenberg J, Belfield J, Ramchandani P, Rocher L, Freeman S, Tsili A . Testicular microlithiasis imaging and follow-up: guidelines of the ESUR scrotal imaging subcommittee. Eur Radiol. 2014; 25(2):323-30. DOI: 10.1007/s00330-014-3437-x. View

20.

Zhang X, Lv F, Tang J . Shear wave elastography (SWE) is reliable method for testicular spermatogenesis evaluation after torsion. Int J Clin Exp Med. 2015; 8(5):7089-97. PMC: 4509191. View