Health Benefits of Fasting and Caloric Restriction

Overview

Journal Curr Diab Rep

Publisher Current Science

Specialty Endocrinology

Date 2017 Oct 25

PMID 29063418

Citations 81

Authors

Saeid Golbidi

Andreas Daiber

Bato Korac

Huige Li

M Faadiel Essop

Ismail Laher

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: Obesity and obesity-related diseases, largely resulting from urbanization and behavioral changes, are now of global importance. Energy restriction, though, is associated with health improvements and increased longevity. We review some important mechanisms related to calorie limitation aimed at controlling of metabolic diseases, particularly diabetes.

Recent Findings: Calorie restriction triggers a complex series of intricate events, including activation of cellular stress response elements, improved autophagy, modification of apoptosis, and alteration in hormonal balance. Intermittent fasting is not only more acceptable to patients, but it also prevents some of the adverse effects of chronic calorie restriction, especially malnutrition. There are many somatic and potentially psychologic benefits of fasting or intermittent calorie restriction. However, some behavioral modifications related to abstinence of binge eating following a fasting period are crucial in maintaining the desired favorable outcomes.

Citing Articles

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Short-Term Fasting Induces Hepatocytes' Stress Response and Increases Their Resilience.

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Liu S, Zhang X, Wang W, Li X, Sun X, Zhao Y Mol Cancer. 2024; 23(1):261.

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Effect of exercise alone and in combination with time-restricted eating on cardiometabolic health in menopausal women.

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