-related Noncoding RNAs in Pancreatic Ductal Adenocarcinoma

Overview

Journal Chronic Dis Transl Med

Publisher Wiley

Date 2017 Oct 25

PMID 29063045

Citations 3

Authors

Shuang-Ni Yu

Yi-Hui Ma

Wu-Gan Zhao

Xiang-Lan Jin

Hai-Yan Yang

Ping-Ping Liu

Jie Chen

Affiliations

Soon will be listed here.

Abstract

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease with a poor overall prognosis. However, curative resection during the early stages of the disease can greatly improve survival rates, highlighting the importance of early screening and detection. Studies of noncoding RNAs, primarily microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), provide important insights into strategies for the early detection of -driven PDAC. Here, we summarize our studies and review current reports on research investigating -related miRNAs and lncRNAs, emphasizing their aberrant expression, mechanisms, carcinogenic effects, and prognostic and predictive capacities in PDAC.

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