The MetaCyc Database of Metabolic Pathways and Enzymes

Overview

Journal Nucleic Acids Res

Publisher Oxford University Press

Specialty Biochemistry

Date 2017 Oct 24

PMID 29059334

Citations 395

Authors

Ron Caspi

Richard Billington

Carol A Fulcher

Ingrid M Keseler

Anamika Kothari

Markus Krummenacker

Mario Latendresse

Peter E Midford

Quang Ong

Wai Kit Ong

Suzanne Paley

Pallavi Subhraveti

Peter D Karp

Affiliations

Soon will be listed here.

Abstract

MetaCyc (https://MetaCyc.org) is a comprehensive reference database of metabolic pathways and enzymes from all domains of life. It contains more than 2570 pathways derived from >54 000 publications, making it the largest curated collection of metabolic pathways. The data in MetaCyc is strictly evidence-based and richly curated, resulting in an encyclopedic reference tool for metabolism. MetaCyc is also used as a knowledge base for generating thousands of organism-specific Pathway/Genome Databases (PGDBs), which are available in the BioCyc (https://BioCyc.org) and other PGDB collections. This article provides an update on the developments in MetaCyc during the past two years, including the expansion of data and addition of new features.

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