Metastasis to the Pancreas and Stomach from a Breast Cancer Primary: a Case Report
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A 60-year-old female with an unknown family history initially presented with signs and symptoms concerning for gastrointestinal cancer. Regular breast cancer screening and subsequent work-up around this time demonstrated the presence of T2N1 stage II triple positive ductal adenocarcinoma of the left breast. Follow-up imaging for her gastrointestinal symptoms demonstrated a 3.5 cm solitary mass in the pancreas and diffuse thickening of the stomach wall. Biopsies of the gastrointestinal lesions were identified as metastatic foci of the breast cancer primary. Breast cancer metastases to the stomach and to the pancreas are both very rare events. Of the breast cancer primaries that do metastasize to the gastrointestinal system, it is unusual for the primary to be ductal adenocarcinoma. The rapid succession of diagnosing the primary source of breast cancer simultaneously with its metastases is also unusual. Timely identification and appropriate management of these rare metastases was made possible due to routine breast cancer screening.
Metastasis to the stomach: a systematic review.
Ibrahimli A, Aliyev A, Majidli A, Kahraman A, Galandarova A, Khalilzade E F1000Res. 2024; 12:1374.
PMID: 38706640 PMC: 11066534. DOI: 10.12688/f1000research.140758.1.
Chen M, Zarrin-Khameh N, Xu Y Cancer Med. 2022; 12(5):5485-5493.
PMID: 36281523 PMC: 10028048. DOI: 10.1002/cam4.5374.
Rare sites of breast cancer metastasis: a review.
Di Micco R, Santurro L, Gasparri M, Zuber V, Fiacco E, Gazzetta G Transl Cancer Res. 2022; 8(Suppl 5):S518-S552.
PMID: 35117130 PMC: 8797987. DOI: 10.21037/tcr.2019.07.24.
Metastasis to the pancreas: a rare site for secondary malignancy of breast cancer (a case report).
Kouhen F, Chihabeddine M, Squali M, Allaoui M, Al Bouzidi A, Errafiy N Pan Afr Med J. 2021; 37:260.
PMID: 33598075 PMC: 7864279. DOI: 10.11604/pamj.2020.37.260.25228.
A rare case report of recurrent metastatic breast cancer mimicking primary pancreatic cancer.
Prakash P, Kit Lee J, Tang S, Iau P Int J Surg Case Rep. 2021; 77:446-449.
PMID: 33395823 PMC: 7691437. DOI: 10.1016/j.ijscr.2020.10.082.