Body Composition Measurement in Young Children Using Quantitative Magnetic Resonance: a Comparison with Air Displacement Plethysmography

Overview

Journal Pediatr Obes

Specialties Endocrinology
Pediatrics

Date 2017 Oct 13

PMID 29024557

Citations 12

Authors

L-W Chen

M-T Tint

M V Fortier

I M Aris

L P-C Shek

K H Tan

V S Rajadurai

P D Gluckman

Y-S Chong

K M Godfrey

M S Kramer

C J Henry

F Yap

Y S Lee

Affiliations

Soon will be listed here.

Abstract

Background: Quantitative magnetic resonance (QMR) has been increasingly used to measure human body composition, but its use and validation in children is limited.

Objective: We compared body composition measurement by QMR and air displacement plethysmography (ADP) in preschool children from Singapore's multi-ethnic Asian population (n = 152; mean ± SD age: 5.0 ± 0.1 years).

Methods: Agreements between QMR-based and ADP-based fat mass and fat mass index (FMI) were assessed using intraclass correlation coefficient (ICC), reduced major axis regression and Bland-Altman plot analyses. Analyses were stratified for the child's sex.

Results: Substantial agreement was observed between QMR-based and ADP-based fat mass (ICC: 0.85) and FMI (ICC: 0.82). Reduced major axis regression analysis suggested that QMR measurements were generally lower than ADP measurements. Bland-Altman analysis similarly revealed that QMR-based fat mass were (mean difference [95% limits of agreement]) -0.5 (-2.1 to +1.1) kg lower than ADP-based fat mass and QMR-based FMI were -0.4 (-1.8 to +0.9) kg/m lower than ADP-based FMI. Stratification by offspring sex revealed better agreement of QMR and ADP measurements in girls than in boys.

Conclusions: QMR-based fat mass and FMI showed substantial agreement with, but was generally lower than, ADP-based measures in young Asian children.

Citing Articles

Prediction of fat-free mass in young children using bioelectrical impedance spectroscopy.

Lyons-Reid J, Ward L, Derraik J, Thway-Tint M, Monnard C, Ramos Nieves J Eur J Clin Nutr. 2023; 78(10):872-879.

PMID: 37524804 PMC: 7616480. DOI: 10.1038/s41430-023-01317-4.

Characteristics of Body Composition Estimated by Air-Displacement Plethysmography in Chinese Preschool Children.

Chen F, Wang J, Liu J, Huang G, Hou D, Liao Z Front Public Health. 2022; 10:926819.

PMID: 35719642 PMC: 9204163. DOI: 10.3389/fpubh.2022.926819.

Association of plasma kynurenine pathway metabolite concentrations with metabolic health risk in prepubertal Asian children.

Mei-Ling Tan K, Tint M, Kothandaraman N, Yap F, Godfrey K, Lee Y Int J Obes (Lond). 2022; 46(6):1128-1137.

PMID: 35173282 PMC: 7612806. DOI: 10.1038/s41366-022-01085-4.

The Kynurenine Pathway Metabolites in Cord Blood Positively Correlate With Early Childhood Adiposity.

Mei-Ling Tan K, Tint M, Kothandaraman N, Michael N, Sadananthan S, Velan S J Clin Endocrinol Metab. 2022; 107(6):e2464-e2473.

PMID: 35150259 PMC: 9113811. DOI: 10.1210/clinem/dgac078.

Breastfeeding may benefit cardiometabolic health of children exposed to increased gestational glycemia in utero.

Ong Y, Pang W, Huang J, Aris I, Sadananthan S, Tint M Eur J Nutr. 2022; 61(5):2383-2395.

PMID: 35124728 PMC: 7613060. DOI: 10.1007/s00394-022-02800-7.

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